Another possible physiological role for a hyperpolarization-activated inward current could be in the postburst hyperpolarization that is characteristic of parasol cells. |
Cordycepin decreases activity of hippocampal CA1 pyramidal neuron through membrane hyperpolarization. |
The former leads to an increase in cyclic adenosine monophosphate and the latter to hyperpolarization, both of which result in relaxation. |
A slight hyperpolarization occurs due to the charge difference between potassium and sodium ions across the membrane. |
Although GABA causes an increased Cl− conductance at these terminals, the result is depolarization, not hyperpolarization, of the membrane. |
Any change in membrane potential tending to make the inside even more negative is called hyperpolarization, while any change tending to make it less negative is called depolarization. |