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What is a founder effect?

What is a founder effect? Here are some definitions.

Noun
  1. (genetics) A lessening of genetic variation when the entire population in question descends from a small number of founders.
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Examples
The differences between replicates possibly result from a founder effect.
Therefore, a wider study assembling 20 N88K mutation-carrying patients from England, Germany and France has just been carried out. It establishes the existence of an ancestral founder effect of this mutation.
A putative founder effect for Parkinson's disease in South African Afrikaners.
This is best explained by a male founder effect during the colonization of northeast India that is estimated to have occurred within the past 4,000 years.
Likewise, founder effect has been discounted as the primary mode of speciation among Darwin's finches since the discovery of extensive MHC variability in these species.
A related phenomenon to the founder effect is what is sometimes called the bottleneck effect.

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