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What does exacerbations mean?

Looking for the meaning or definition of the word exacerbations? Here's what it means.

Noun
  1. plural of exacerbation
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Dr. Kuna and colleagues report an uncommon cause of asthma exacerbations after unprotected coitus in a 48-year-old male.
These findings reflect the continually worsening nature of the disease rather than consequences of exacerbations.
Shorter courses of steroids may be followed by severe rebound exacerbations shortly after drug therapy is discontinued.
Human rhinovirus, which results in a nonlylic upper respiratory tract infection, is the dominant cause of virus-induced asthma exacerbations.
The syndrome is cyclic with exacerbations and remissions occurring in a randomized pattern.
Asthma in young children is no longer considered a benign disease, since it often presents with acute exacerbations.

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