| More specifically, they show that the landscape generator performs best with low configurationally structured reference projects and performs less with high configurationally structured reference projects. |
| Studies are therefore being carried out to increase the configurationally stability of such lithium reagents. |
| Currently, we are studying thiospiropyran and spirooxazine derivatives which should be configurationally much more stable than the corresponding spiropyrans. |
| In most cases, the biaryl axis is configurationally stable and represents an additional element of chirality. |
| The enantiomers are configurationally unstable in vitro or undergo racemization in vivo. |
| These configurationally constrained molecules have led to the design of a novel class of benzodiazepine VLA-4 antagonists. |
