One hundred randomly selected metaphase cells were scored for the presence of chromatid gaps and breaks. |
We observed 28 breaks of the chromatid type, 13 of chromosome type and 10 dicentrics. |
In anaphase each chromatid pair separates into two identical chromosomes that are pulled to opposite ends of the cell by the spindle fibres. |
A double crossover involving one linear chromatid and both chromatids of the circular chromosome generates a linear trimer. |
Gap: an achromatic lesion smaller than the width of one chromatid, and with minimum misalignment of the chromatids. |
These effects include the induction of chromosomal aberrations and sister chromatid exchange. |