Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions. |
Chlorambucil is an effective corticosteroid-sparing agent for recalcitrant pyoderma gangrenosum. |
Methotrexate and chlorambucil have been used as steroid-sparing agents, but have toxicities of their own. |
Moreover, it is used in combination with chlorambucil, a known teratogen. |
The patient's treatment included chlorambucil and radiolabeled rituximab. |
Combinations of chlorambucil, Prednisone or cyclophosphamide and a new drug Fludarabine are used in treatment. |