Additional granulocytes are attracted and directed to the sites of infection in a process called directed migration, or chemotaxis. |
The formation of pseudopods and lamellae after ligation of chemoattractant sensitive G-protein coupled receptors is essential for chemotaxis. |
In general, the response of the leukocytes to chemotaxis is a conservative process. |
Non-phagocytic leukocytosis is probably due more to stimulation of blood-making organs than to chemotaxis. |
These include regulation of collagen synthesis, inflammatory cell chemotaxis, and DNA synthesis. |
The evidence for a direct effect of macrolides on neutrophil chemotaxis is conflicting. |