| We define primary bronchiolar disorders as those diseases in which an isolated pathologic process is limited to bronchioles anatomically. |
| The TNF-alpha gene is regulated by the surfactant protein C promoter, which is active in bronchiolar and alveolar type 2 cells. |
| Weak immunoreactivity for NOS2 in the normoxia plus saline group was present in bronchiolar and vascular smooth muscle, bronchiolar epithelium, and Clara cells. |
| Large continuous masses of eosinophils were situated within the extracellular matrix, beneath the bronchiolar smooth muscle layer. |
| The development of pulmonary interstitial fibrosis is preceded by injury to the alveolar and bronchiolar epithelium. |
| From the pathophysiological point of view, respiratory failure occurs due to irreversible obstruction of the bronchiolar regions. |
