In the case of PNPO deficiency, plasma AADC activity can be increased, probably owing to upregulation of apoenzyme synthesis in the absence of the PLP cofactor. |
During preincubation the apoenzyme and hematin form the active holoenzyme. |
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure. |
A cofactor that is bound loosely to the apoenzyme and can be readily separated from it is called a coenzyme. |