| Most forms of gout can be treated by administering the antimetabolite, allopurinol. |
| A product containing an alkylating anthracycline of formula Ia or Ib: and an antimetabolite compound as a combined preparation for simultaneous, separate or sequential use in the treatment of tumors. |
| An antimetabolite is similar in structure to a metabolite, or enzymatic substrate, which is normally recognized and acted upon by an enzyme to form a substance required by the cell. |
| Thioguanine is a close relative of mercaptopurine and like the latter is an antimetabolite which blocks purine metabolism. |
| In 1956 the antimetabolite methotrexate became the first drug to cure a solid tumour, and the following year 5-fluorouracil was introduced as the first of a new class of tumour-fighting compounds known as pyrimidine analogs. |
| Clofarabine, a type of drug called a purine nucleoside antimetabolite, works by blocking the production and repair of DNA, the building blocks of genes. |
