Other research projects cover melanoma, adrenocortical tumours, head and neck squamous cell carcinoma, and bladder cancer. |
Increased secretion of ACTH because of a corticotroph tumour or corticotroph hyperplasia causes adrenocortical hyperfunction, which in turn causes the constellation of symptoms and signs called Cushing syndrome. |
The available evidence is inadequate to confirm if dexmedetomidine is associated with significant adrenocortical suppression. |
Lastly, polycythemia can develop in the presence of certain types of tumours and as the result of the action of adrenocortical secretions. |
Adrenocortical hyperplasia and adrenocortical neoplasms have pleomorphic mitochondria with tubulovesicular and lamelliform cristae and occasional inclusions. |
For those treated by pituitary surgery, irradiation, or other measures and for those who spontaneously develop deficits of gonadal, thyroidal, or adrenocortical hormones, replacement-hormone therapy is necessary. |