| Two larger pieces consisted of clearly nondysplastic squamous epithelium with glycogenic acanthosis. |
| Obesity, acne, hirsutism, and acanthosis nigricans may be signs of polycystic ovary syndrome or diabetes mellitus. |
| Patients are often concerned about the physical manifestations of this disorder, including virilization and acanthosis nigricans, and may be less aware of systemic problems. |
| Hi stological examination of the lesions typically reveals hyperkeratosis with or without parakeratosis, acanthosis, and enlargement of the rete ridges. |
| Glycogenic acanthosis is a common degenerative condition characterized by accumulation of cytoplasmic glycogen in the squamous epithelium of the esophagus. |
| From the perspective of the gastroenterologist, the presence of glycogenic acanthosis and hamartomatous polyps should suggest the diagnosis of Cowden's syndrome. |
