The two domains are connected by a stretch of unstructured amino acids which functions as a flexible linker. |
The effect of the proline insertions on the linker stiffness is, however, unclear. |
Therefore, the given stiffness values provide an effective description, obtained from sampling many different linker conformations. |
The shorter linker would render the channel hypersensitive to stretch or prevent complete closure. |
Linker graduated from Elmira High School in 1956, and lived in Veneta, Springfield and Eugene most of her life. |
Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. |