Secondary replication occurs in the liver and spleen, with secondary viremia leading to viral invasion of the dermal capillaries and epidermis. |
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Infection is often subclinical, manifested as asymptomatic viremia or shedding of virus in the respiratory tract or urine. |
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Immunocompromised patients may have persistent viremia, larger lesions, purpura, and systemic involvement. |
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In these cases, viremia was assessed by virus culture in serum and lung tissues at necropsy. |
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Primary viremia causes dissemination of the virus in lymphoid tissues throughout the body. |
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By the time the rash or polyarthropathy presents in immunocompetent patients, viremia has cleared and the presence of serum antibodies confirms the diagnosis. |
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Because viremia lasts for 6.2 days on average, 4 infected donors can contribute only 25 days of viremia. |
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Even with the information from past epidemics, screening for viremia will be stringent and surveillance will continue. |
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It is estimated that in humans, viremia begins 1 to 2 days after infection, with symptoms developing 2 to 15 days after infection. |
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Several unknowns e.g. period of viremia, infectious dose, prevalence in donors, transfusion transmission incidence rate etc. |
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Two possible medical courses of action might be prescribed: watchful waiting, or more in depth investigation which could go the extent of testing for viremia which involves much more severe constraints. |
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Once there is detection of BK viruria and viremia, the treatment strategy for BKV infection is not uniform and will need further investigation. |
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Availability of activated CD4 T cells dictates the levels of viremia in naturally SIV-infected sooty mangabeys. |
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Degree of fatigue does not correlate with presence or level of viremia, does not correlate with ALT levels or degree of inflammation or fibrosis on histology. |
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In late hemorrhagic cases, high and sustained viremia, severe platelet loss and poor immune response were often cited as causes of death. |
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Three months after admission, the patient had viremia, and results of liver function tests were abnormal. |
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The degree of a patient's viremia correlated positively with the percentage of epithelial sweat gland cells that were infected, she noted. |
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These samples were analyzed by qRT-PCR and IgM-capture ELISA to detect viremia and IgM, respectively. |
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Circulating immune complexes, overwhelming viremia, or an uncontrolled immune response may be contributing factors. |
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However, WNV viremia was sufficient, in theory, to infect mosquitoes, and oral and cloacal shedding of the virus may increase the risk of infection to other waterbirds. |
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Viremia does not develop in most passerine birds, which are not able to pass the virus to ticks. |
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