However, neither fenvarelate nor veratridine affected the antinociceptive effect of fentanyl in non-diabetic mice. |
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Figure 7 shows a recording from contracting skeletal muscle before and after the addition of veratridine. |
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Pretreatment with either of the voltage-gated sodium channel openers fenvarelarte and veratridine practically abolished the antinociceptive effects of fentanyl in diabetic mice. |
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Subsequently, Nav channel activity was studied using veratridine. |
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Like batrachotoxin and veratridine, grayanotoxins act at the voltage-dependent sodium channel in its open conformation, inhibiting its inactivation. |
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