| The human reovirus infects and kills cancer cells with an activated Ras pathway. |
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| As such, recent research has focused on reovirus type 3 and cytomegalovirus as possible viral agents. |
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| The MSU M Cell vaccine technology that has been licensed by LigoCyte is based on the targeting of mucosal M-cells using a protein isolated from reovirus. |
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| The claims cover methods of selectively removing cancer cells ex vivo from blood stem cells and other organs using reovirus. |
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| Oncolytics Biotech has been developing a method of utilizing a reovirus to target and kill cancers that exhibit mutated RAS pathway activity. |
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| The investigators tested reovirus in vitro against recently resected colorectal cancer liver metastases. |
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| The claims describe methods of using the reovirus ex vivo to eliminate contaminating cancer cells from autologous blood stem cell transplants. |
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| This article describes the characterization of 4 double-stranded ribonucleic acid segments, S1, S2, S3, and S4, of a newly identified pathogenic reovirus from parrots. |
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