| And it isn't clear how much of that research would meet the gold standard in clinical research, the controlled, randomised, double-blind trial. |
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| We included nine randomised controlled trials eight of which compared a lactam antibiotic with a lactam and aminoglycoside. |
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| This was illustrated in a randomised trial of screening for cancer of the lung. |
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| Following up the placebo arm of a randomised trial can be a good way of tracking the course of benign diseases. |
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| Most randomised trials allocate individual participants to different treatments. |
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| This evidence led to a multicentre randomised controlled trial in women with osteoporosis. |
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| The trial was a multicentre, pragmatic randomised controlled trial stratified by centre. |
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| This is the first multicentre randomised trial including more than 1500 patients followed for more than a year. |
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| Few randomised trials exist that directly compare supervised and unsupervised exercise training. |
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| The current absence of evidence from randomised trials should not be used as an excuse for neglecting basic care for patients with stroke. |
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| This randomised study is often seen as having ushered in a new era in making fair comparisons of alternative treatments. |
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| The results also validate previously reported randomised controlled trial data. |
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| Adding vitamin A to foods is one way around the problem, although few fortified foods have been tested in randomised trials. |
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| We randomised patients individually using sealed, opaque, sequentially numbered envelopes. |
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| In this paper we use statistical techniques to examine data from two randomised controlled trials. |
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| We did find information in the form of randomised controlled trials of tetrahydrocannabinol and synthetic cannabinoids. |
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| We stratified patients in each centre according to degree of obstruction and randomised them to treatment by consecutive sealed opaque envelopes. |
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| Mothers were then randomised to the intervention or control group within two strata. |
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| Some insects even cultivate chaotic output to produce randomised behaviour. |
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| This review summarises the evidence from randomised controlled trials of the effectiveness of exercise as a treatment for depression. |
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| We randomised patients managed by general physicians and general practitioners, who care for most people with chronic heart failure. |
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| In the first phase, more patients are randomised to placebo than to active treatment. |
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| This finding was confirmed by a study that randomised 112 patients to treatment or placebo. |
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| We reduced confounding variables by using a randomised crossover trial and the same browser for searching both schemes. |
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| The study was a randomised double blind placebo controlled crossover trial. |
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| Data from 10 schools participating in a group randomised controlled crossover trial were pooled and analysed. |
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| Most prospective cohort studies and randomised controlled trials today include only individuals who are followed to observe outcomes. |
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| Our study was designed as a prospective, randomised, double blind, placebo controlled trial. |
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| Could a randomised trial answer the controversy relating to elective caesarean section? |
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| Infants randomised to the dummy groups received a dummy on entry into the trial. |
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| They critically reviewed 12 randomised trials, five of which reported benefits from strength and balance training, endurance training, or t'ai chi. |
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| A recent large multicentre randomised controlled trial of botulinum toxin for glabellar lines showed a significant reduction in the lines compared with placebo. |
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| In principle, considerations about generalisability should not affect the internal validity inherent in a well performed randomised controlled clinical trial. |
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| A multicentre randomised controlled trial of routine antenatal care by general practitioners and midwives compared with shared care led by obstetricians. |
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| However, only single randomised controlled trials for each of the tested interventions were available, most were of small sample size, and all used unvalidated symptom scores. |
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| Technical limitations in the current study meant that the order in which the homophones were presented could not be separately randomised for each participant. |
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| No randomised trials were identified that studied the efficacy of carbon dioxide laser, surgical excision, curettage or cautery, formaldehyde, podophyllin, or podophyllotoxin. |
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| When there is no direct randomised evidence, the adjusted indirect method may provide useful information about relative efficacy of competing interventions. |
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| To identify effective interventions and their relative effectiveness in preventing such falls, we conducted a meta-analysis of relevant randomised controlled trials. |
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| Hence, we concluded that unless studies give much more extreme relative risks, randomised trials of anti-infective interventions may be needed to help determine causality. |
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| It is possible to conceal the randomisation in every randomised trial. |
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| One of the largest studies was the child and adolescent trial for cardiovascular health study, which randomised 4019 children representing many ethnic groups. |
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| Policy makers should consider testing health service innovation using cluster randomised controlled trials with the hospital as the sampling unit. |
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| Investigators responsible for trials that had randomised fewer than 200 patients were asked only for the tabular summary of the numbers of patients and outcomes. |
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| Pooled individual data analysis of five randomised trials of infant nevirapine prophylaxis to prevent HIV-1 transmission through breastmilk. |
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| They cite two randomised trials for total knee arthroplasty with 20 patients in each treatment arm. |
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| The authors selected randomised and non-randomised controlled studies with outcomes of perinatal, neonatal, and maternal mortality. |
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| A randomised trial of the impact of new faecal haemoglobin test technologies on population participation in screening for colorectal cancer. |
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| Laryngoscopies were performed using a size 3 MAC laryngoscope and a GVL in a randomised sequence. |
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| A prospective randomised controlled trial of ultrasound guided versus nerve stimulation guided distal sciatic nerve block at the popliteal fossa. |
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| This was a randomised, double-blind clinical trial comparing the efficacy of ginger with sumatriptan in treatment of migraine. |
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| A multifactorial intervention for the prevention of falls in psychogeriatric nursing home patients, a randomised controlled trial. |
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| They looked at 1 709 patients with a history of stroke or transient ischaemic attack randomised to fixed doses of perindopril and indapamide. |
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| A multicentre randomised study of warfarin or heparin after a Fontan procedure was reported. |
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| Lewith GT, Machin D A randomised trial to evaluate the effect of infra-red stimulation of local trigger points, versus placebo, on the pain caused by cervical osteoarthrosis. |
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| In a single blind randomised control pilot study, curcuminoids or placebo was administered orally, 2 grams twice daily to a cohort of 26 MGUS patients. |
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| Prospective randomised study of urgent haemorrhoidectomy compared with non-operative treatment in the management of prolapsed thrombosed internal haemorrhoids. |
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| Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients. |
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| Patients were randomised to ginger root powder capsules or placebo capsules as an additional antiemetic to ondensetron and dexamethasone in a double blind design. |
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| The BMJ published the first centrally randomised controlled trial. |
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