| The prothrombin test is one measure of how long it takes your blood to begin clotting. |
|
| Contact with tissue factor triggers the coagulation cascade, resulting in the conversion of prothrombin to active thrombin. |
|
| The atrial fibrillation group also had more hematologic tests done, including more prothrombin and partial thromboplastin times. |
|
| The next to last step in this chain is the activation of the circulating proenzyme prothrombin into its active form, thrombin. |
|
| In the second stage, prothrombin is activated by thromboplastin to make thrombin. |
|
| This complex activates prothrombin to thrombin in the presence of calcium ions. |
|
| Patients treated with a proton pump inhibitor and warfarin concomitantly may need to be monitored for increases in INR and prothrombin time. |
|
| Tests of clotting function include such indicators as the prothrombin time and the partial thromboplastin time. |
|
| The platelet count and sedimentation rate were normal, but the prothrombin time and activated partial thromboplastin time were prolonged. |
|
| This test measures prothrombin time and is ordinarily performed at the anticoagulation therapy clinic. |
|
| If coadministration is necessary, the prothrombin time or INR should be carefully monitored upon antibiotic addition or withdrawal. |
|
| Years ago we said fibrinogen becomes a clot of insoluble fibrin by the action of thrombin made from soluble prothrombin in the presence of calcium. |
|
| The tests that are performed are a complete blood count, blood chemistry, prothrombin time, partial thromboplastin time, electrocardiogram, and chest x-rays. |
|
| Indicated tests include a complete blood cell count with platelet count, a peripheral blood smear, and prothrombin and activated partial thromboplastin times. |
|
| Disseminated intravascular coagulation was based on prothrombin time, activated partial thromboplastin time, and d-dimers. |
|
| The activity of the extrinsic pathway may be assessed in the laboratory using a simple test known as the prothrombin time. |
|
| This form of prothrombin deficiency can be prevented by administration of vitamin K to the baby shortly after birth. |
|
| Increases in INR and prothrombin time may lead to abnormal bleeding and even death. |
|
| Prolongation of bleeding time and prolongation of prothrombin time have also been reported. |
|
| Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time. |
|
|
|
| There have been reports of increased INR and prothrombin time in patients receiving proton pump inhibitors, including rabeprazole, and warfarin concomitantly. |
|
| In case of coadministration, prothrombin time should be more frequently monitored and anticoagulant therapy adjusted during treatment with Flagyl. |
|
| In addition, EZETROL® had no effect on the plasma concentrations of the fat-soluble vitamins A, D, and E, or on prothrombin time, and did not impair adrenocortical steroid hormone production. |
|
| The clotting proteins that function as zymogens in the blood include factor XII, factor XI, prekallikrein, factor IX, factor X, factor VII, and prothrombin. |
|
| Pre-albumin, C1-esterase inhibitor, haptoglobins, transferrin, antithrombin III, prothrombin and plasminogen were all shown to increase following administration of danazol. |
|
| Platelet counts, prothrombin times and partial thromboplastin time have been reported to be significantly greater in treated than in control animals, although all values have been within accepted normal ranges. |
|
| Prolongations in prothrombin time and activated thromboplastin time were associated with clinical, hematologic, and pathologic evidence of hemorrhage in dogs. |
|
| In most dose groups of the various animal models tested, studies showed dose-related decreases in prothrombin and activated partial thromboplastin times, and treatment-related increases in fibrinogen. |
|
| The major areas of toxicity identified in the acute and chronic toxicity studies include prolongation of activated partial thromboplastin and prothrombin times, liver effects, thyroid effects, and gastrointestinal effects. |
|
| Reports of decreased prothrombin, increased INR and unbalanced anticoagulant treatment resulting in change of haemostatic parameters have been reported in patients treated concomitantly with orlistat and anticoagulants. |
|
| Vitamin K is necessary for the formation of prothrombin and other blood-clotting factors in the liver, and it also plays a role in bone metabolism. |
|
| Their analysis focused on prothrombin time and activated partial thromboplastin time results. |
|
| These reactions have sometimes been associated with abnormalities of coagulation tests such as clotting time, platelet aggregation, and prothrombin time, and are more likely to occur in patients with renal failure. |
|
| Due to the narrow therapeutic index, close monitoring of increased or decreased prothrombin time is recommended during concurrent treatment with ranitidine. |
|
| A prothrombin mutation, also known as factor II mutation, causes the body to produce too much of the prothrombin protein, which makes blood more likely to clot. |
|
| The fi nal common pathway of the clotting cas cade converges on activation of Factor V, which converts prothrombin to thrombin. |
|
| Preoperative coagulation parameters, including prothrombin time, aPTT, INR and fibrinogen were normal. |
|
| How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults. |
|
| Serum biochemistry, erythrocyte sedimentation rate, C-reactive protein, bleeding time, prothrombin time and activated partial thromboplastin time were within normal limits. |
|
| However, it was noted that for six out of the twelve patients, catheter removal was delayed to the fifth or sixth postoperative day due to a prolonged prothrombin time. |
|
|
|
| Furthermore, a genetic factor that increases the risk of VTE G20210A variation in the prothrombin gene associated with elevated plasma prothrombin level has been described. |
|
| Prothrombin time and partial thromboplastin test kits from Qumica Clinka Applicada Spain were used in the study. |
|
