| In response to infectious pathogens or their by-products, monocytes and macrophages generate and release proinflammatory cytokines. |
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| However, proinflammatory cytokines and chemokines have been previously implicated in this process. |
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| Type II epithelial cells are said to play a major role in the inflammatory process in the lungs by production of proinflammatory cytokines. |
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| The effects were much more noticeable for ultrafine nickel, particularly in the release of proinflammatory cytokines for 30 days post-exposure. |
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| In a deficiency state, this blockade in normal metabolism could result in the preferential production of proinflammatory eicosanoids. |
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| The nitration and oxidation injury from the microglial proinflammatory response promotes a vicious cycle of continued oxidative neural injury and microglial activation. |
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| It has been proposed that the large amounts of heme in the blood stream stimulate a proinflammatory state. |
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| Through inhibition of the cyclooxygenase pathway of arachidonate metabolism, NSAIDs prevent the production of the proinflammatory prostaglandins. |
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| Eplerenone produced cardioprotective effects in animal models of hypertension in part by attenuating proinflammatory molecule expression in the heart and by reducing subsequent vascular and myocardial injury. |
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| These studies suggest that high BACs, proinflammatory cytokines, and neurodegeneration may be significant contributors to alcoholism. |
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| Our results suggest that ZNF395 contributes to hypoxia associated inflammation by superactivating proinflammatory cytokines. |
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| Superimposed and contributory to the insensitivity to insulin produced by excessive free fatty acids is the paracrine and endocrine effect of the proinflammatory state. |
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| Lead scientist Rama Natarajan, Yan Li, and colleagues set out to determine the DNA mechanisms linking specific enzymes and the activation of proinflammatory genes associated with diabetes and its complications. |
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| Both B cells and T cells form aggregates in the synovium of joints and mediate the pathogenesis of RA and proinflammatory cytokines, which are critically involved. |
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| Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp7OB' in human keratinocytes modulating the proinflammatory response. |
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| We suggest this increase might probably be generated in an effort to counteract the already increased concentrations of proinflammatory cytokines. |
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| This study explored how conflicts between members of a couple may affect wound healing and local and systemic proinflammatory cytokine production. |
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| Thus, the nucleus pulposus appears to have inflammatory properties and creates pain by sensitizing nerve tissues, possibly through the production of proinflammatory cytokines. |
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| Proinflammatory cytokines and chemokines were measured in lung homogenates. |
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