| With this low level of presynaptic stimulation, quantal currents could be resolved. |
|
| It does so by blocking the normal presynaptic reuptake, causing an increase in function or activity level of these transmitters. |
|
| Molecular features of the phasic and tonic presynaptic nerve terminals are currently under investigation. |
|
| Most of the clinically significant symptoms of dissociatives are produced by presynaptic dopamine stimulation and cholinergic antagonism. |
|
| The properties of the presynaptic neuron can also be influenced by the cell with which it makes a synapse. |
|
| Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron. |
|
| Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft. |
|
| The release of neurotransmitter is variable and dependent on the properties of the presynaptic terminal. |
|
| The toxin irreversibly binds to presynaptic cholinergic receptors at motor nerve terminals and is subsequently internalized. |
|
| The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems. |
|
| Postsynaptic proteins receive the neurotransmitters released by presynaptic proteins. |
|
| Instead, transmission is accomplished by the release of a chemical neurotransmitter substance from the presynaptic fibre. |
|
| A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities. |
|
| The authors proposed a mechanism of action whereby the calcium channel blocker inhibited the presynaptic release of neurotransmitters. |
|
| The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings. |
|
| From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered. |
|
| As a nerve impulse, or action potential, reaches the end of a presynaptic axon, molecules of neurotransmitter are released into the synaptic space. |
|
| This local depolarization is known as an excitatory synaptic potential, and its amplitude is determined by the number of vesicles released from the presynaptic cell. |
|
| The brightness and density of mito-GFP labeling within presynaptic boutons provides a rough estimate for mitochondrial concentration in the presynaptic axoplasm. |
|
| This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell. |
|
|
|
| To transmit a nerve impulse, the presynaptic neuron secretes a chemical messenger called a neurotransmitter. |
|
| The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons. |
|
| Second, they are taken back into the presynaptic terminal by transmitter-sensitive transport molecules. |
|
| Investigating the effect of presynaptic doses of apomorphine on declarative memory in normal subjects. |
|
| Juxtaglomerular cells showed similar excitatory odorant response profiles to presynaptic olfactory sensory neuron inputs. |
|
| For this change to occur, the presynaptic and postsynaptic neurons must be activated during the release of dopamine. |
|
| Unlike the classic neurotransmitters described above, which are formed by enzymes near the presynaptic terminals, neuroactive peptides are assembled by ribosomes attached to the endoplasmic reticulum. |
|
| The presynaptic terminal is unmyelinated and is separated from the neuron or muscle cell onto which it impinges by a gap called the synaptic cleft, across which neurotransmitters diffuse when released from the vesicles. |
|
| Synapsins are a group of neuronal-specific phosphoproteins that are important regulators of synaptic vesicle trafficing in presynaptic terminals. |
|
| The membrane of a postsynaptic fibre has many different kinds of receptors, and some presynaptic terminals release more than one type of neurotransmitter. |
|
| Amphetamines are thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. |
|
| In experimental animals, repeated or prolonged stress could lead to hyposensitivity of D2 presynaptic receptors. |
|
| Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains. |
|
| When a nerve impulse reaches the end of the motor neuron, ACh is released from the presynaptic nerve ending into the synaptic cleft. |
|
| However, the increase in excitability as a mechanism of retention does not depend on the coactivity of presynaptic and postsynaptic neurons. |
|
