This is a precursor of the modern Spaghetti alla carbonara, one of the most popular pasta dishes, but of obscure origin. |
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The early stages of mineralization of bone tissue proceed through the formation and growth of bioapatite crystallites from a precursor material. |
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Companies can be guided by key lead indicators which have historically been a precursor of a change in activity levels for their business sector. |
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This suggested that marijuana use was not a necessary precursor to use of crack, powder cocaine, or heroin. |
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Tryptophan is used in some plant species as a precursor to bioactive alkaloids and defence phytoalexins, as well as the phytohormone auxin. |
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We investigated a role of the glyoxalase detoxification system of precursor reactive carbonyl compounds in the in vivo AGE formation. |
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These precursor cells give rise to all of the mature oligodendrocytes that make myelin throughout life. |
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If there's a literary precursor, it's the English 17th century essayist Sir Thomas Browne. |
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Bond's preoccupation with brand names made him a precursor of the consumer society. |
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In fact, the form of old Celtic was the closest cousin to Italic, the precursor of Latin. |
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On the one hand, alchemy is regarded as a precursor of the modern science of chemistry. |
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Not only is the construction different from Stonehenge, but it is also a precursor. |
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The bear hug is a dominant position, with great control over the opponent, and is often a precursor to a takedown. |
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The problem in the United States is that law enforcement tends to monitor the purchase of the precursor chemicals required to synthesize ecstasy. |
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In another passage Weber defines the tasks of economic history as a precursor of neoclassical cliometrics. |
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This union of chemistry with medicine was one characteristic of the iatrochemical school of which he was the precursor. |
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A modern and widespread alternative or precursor to marriage is cohabitation. |
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Recognizing the indemonstrable is a necessary precursor to understanding the nature of a parable. |
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This took place in 1922, and was a precursor of the show trials of the following decades. |
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In the Netherlands, shared care models have acted as a precursor of the recently introduced concept of disease management. |
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In so doing, Coram created London's first art gallery, a precursor of the Royal Academy. |
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It was an obvious precursor of today's great intermediary, money, in such forms as bank credit. |
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The folic acid pathway provides the essential precursor molecule, pyridine thymidylate, needed in DNA biosynthesis. |
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As the first venture develops it is the precursor of what may become a new niche in the travel industry and in holiday home real estate. |
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Once inside a cell, cystine is rapidly reduced to cysteine that, as a precursor of GSH, undergoes GSH synthesis. |
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He was able to reverse this effect by giving the animals dopa, the amino acid precursor for dopamine. |
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This monologue dates from 1977, and it is perhaps most interesting as a precursor of the author's later and better work. |
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This suggests derivation from a sedimentary precursor in which zircons would reflect recycling and abrasion during sedimentary processes. |
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Globular theories, the precursor to the cell theory, were quite popular at the beginning of the 19th century. |
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Only Richard Hooker can count as a precursor, and then merely in one limited branch of philosophy, that of jurisprudence. |
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Eiji and Ohno came up with the kanban system of labeling, an early precursor to bar codes, to keep the flow of parts smooth. |
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The precursor of books to follow for the next 200 years, he published it in four volumes in 1694 and it later went through at least ten editions. |
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The bond systems of the invention are generally made by combining at least a curable binder precursor with hard, inorganic particulates. |
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The behavior you describe is a classic precursor for even worse emotional abuse and could possibly turn violent. |
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Such opportunities are occasionally used as a precursor for stalking or worse. |
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The three types of fibrils chosen for investigation represent extremes of precursor proteins that self-assemble into amyloid. |
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The dopamine precursor levodopa is the most common treatment for Parkinson's disease. |
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Based on the above, he was able to conclude that the immediate precursor of cuneiform writing was a system of tokens. |
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For the moment, however, Wood is in rude health and enjoying a tour he sees as a precursor to greater things ahead. |
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He focused on her Depression-era photographs and early work for the magazine, viewing Mieth as a precursor to later social documentarians. |
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The astragalus, a precursor to the die made from the knuckle bone of animals, was found in archeological sites of early peoples. |
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It is a necessary precursor of the estradiol, androsterone, and other hormones. |
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These collisions result in subsequent fragmentation and product ions that are a direct consequence of dissociation of the precursor ion. |
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The rest are nuclear-encoded and are synthesized as precursor proteins on free cytosolic polysomes. |
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The pre-meal selection of chutneys is a precursor of the sharp flavours to come. |
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Chronic stimulation of the receptor causes an increase in the synthesis of a major thyroid hormone precursor, thyroglobulin. |
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Stem cells are precursor cells that can proliferate, differentiate, and self-renew. |
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Tryptophan is an amino acid that serves as a precursor to the neurotransmitter serotonin. |
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Unlike the single chain precursor of insulin, proinsulin, this new construct retains up to 40 per cent of insulin activity. |
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As students speculate, stop and contemplate, little evidence to its precursor can be found. |
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This is performed largely by the enzyme plasmin, generated from its inactive precursor, plasminogen. |
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This is a touchy topic, and not just because people tend to assume that understanding is a precursor to forgiveness. |
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Each superfamily is clearly divisible into two to four distinct families on the basis of conserved elements in the precursor sequences. |
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What appeals to me is that it's a precursor of Pinter and a follower of Coward. |
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The ephedra plant, from which the precursor of methamphetamine is made, grows wild in northern China. |
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Undoubtedly, this increasingly common practice was a precursor to the widespread adoption of the double-entry system. |
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Such an association of cells and mechanism of precursor translocation have not been reported from nemerteans previously. |
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For us young'uns Kate Bush is remembered, vaguely, as a kind of precursor to Tori Amos, a similarly cryptic and leftfield songstress. |
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Most researchers have identified British reliance on fingerspelling as at least a precursor to oralism. |
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Chiefdoms characteristically have an ideology, precursor to an institutionalized religion, that buttresses the chief's authority. |
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We eat pancakes only once a year, as a luxury pig-out and as a precursor to 40 days of being good. |
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It was the precursor to the Seventies with their hopeless mismanagement of government and spinelessness towards terrorism. |
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Procalcitonin, the precursor molecule of calcitonin, is a 116-amino acid peptide that is devoid of known hormonal activity. |
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Meat contains cholesterol, a precursor to many hormones, including testosterone. |
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Centuries later the Elizabethans and Jacobeans thought of Sluys as a historical precursor to the Spanish Armada. |
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Evidence suggesting the existence of multiple import pathways at the outer envelope membrane for different classes of precursor proteins has been presented. |
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Insulin resistance, a condition in which the body handles glucose poorly because cells respond inefficiently to insulin, is a precursor to type II diabetes. |
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Ambulocetus apparently swam much like an otter, with an up-and-down motion of the spine, the precursor to the motion of the flukes of a whale's tail. |
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That convention, though poorly attended, was the precursor to the Constitutional convention. |
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If you thought the precursor, House of 1,000 Corpses, was the equivalent of drinking the contents of a used barf bag, you may want to steer clear of this gruesome follow-up. |
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Schedule 3 comprises a number of toxic or precursor chemicals with widespread industrial uses, such as phosgene, hydrogen cyanide, phosphorus trichloride and thionyl chloride. |
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Here, the blockage of RNA prevents extra amyloid from being produced by targeting its precursor protein and making less of it. |
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Thunder and lightning, therefore, could be viewed either as the voice of the vengeful prophet chasing demons or as the precursor of rain for thirsty crops. |
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The oil droplets contain a molecular metal oxide precursor, which polymerises on contact with water forming a polymeric metal oxide coating at the oil-water interface. |
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It is indispensable for electrofusion, being essentially its precursor. |
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The aspartate can be used as a precursor for the synthesis of other amino acids such as asparagine, threonine, isoleucine, leucine, valine, lysine, and methionine. |
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Later performances took the concept further with U Roy toasting over Tubby's dubs in a manner that obviously pinpoints dub as a key precursor to DJ and rap styles. |
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The result for Milne's cosmology was a stationary universe with an infinite past age which, of course, acted as a precursor to the steady-state theory. |
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Also mixed in the melange are sandy limestone and serpentine, as well as sediments that eroded off a precursor of our present Sierra Nevada Range. |
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The New York Dolls, as characterized by Hermes, were not a satellite New York phenomenon, but a precursor to the punk movement. |
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However, its immediate precursor compound, thiodiglycol, is used industrially, although in quantities that don't come anywhere near chlorine or phosgene. |
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For PSD analysis, the reflector voltage was stepped down in 10 to 12 steps, starting from 30 kV, in order to collect fragment ions from the precursor down to immonium ions. |
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As in so much else, the French revolutionary regime was the precursor of the centralized, totalitarian, managerial, pseudo-democratic despotisms that now reign over the West. |
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They were a precursor to modern mines, high-explosive devices that can be detonated by the completion of an electrical circuit, by pressure, or by a tripwire. |
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If yesterday's purchase of shares is the precursor to a takeover bid, those qualities will make them formidable opponents for the Manchester United board. |
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Hall validated her observations by staining the cells with various antibodies that only bind to and illuminate proteins unique to oligodendrocytes precursor cells. |
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In this way, the anti-modern currents running through woodcraft served as a precursor to the broad critique of modernity that inspired the interwar years wilderness movement. |
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The truly great thing about this record is that it's accessible to anyone as mood music, but also stands strong as a bookend to its earthier precursor. |
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Insulin is synthesized as a precursor, preproinsulin, and after removal of the signal peptide, proinsulin folds to form the correct tertiary structure. |
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In general, a quasi-crystalline boehmite precursor and an additive are converted to a quasi-crystalline boehmite containing the additive in a homogeneously dispersed state. |
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A unilinear view of modernity, with Shitao's gestural brushwork as a sort of unconscious precursor to Abstract Expressionism, is here surely laid to rest forever. |
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These results suggested that possible precursor viruses for highly pathogenic avian myxoviruses are still brought into Japan by migratory waterfowls. |
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Hubris has most clearly set in and hubris is the precursor of the end. |
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If there is any likeness at all between the machine and its embodied precursor, the closest analogy to that relationship might be between adults and the babies they once were. |
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In all tetrapods, LPFs in the environment result in release of adrenocorticotropin from the precursor molecule pro-opiomelanocortin in the anterior pituitary. |
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Urate in blood plasma is a precursor of these uric acid crystals. |
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The global category needs to be unpacked to incorporate local heterogeneity of agricultural and social form as a precursor to understanding situated processes of change. |
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The validation of his claim is a precursor to progressing discussions. |
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The broad spectrum serine protease plasmin is formed following cleavage of the zymogen precursor plasminogen by host activators tissue plasminogen activator and urokinase. |
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What could audiences possibly gain from watching Hollywood personnel go through the motions of adhering to an Asian precursor? |
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In fact, of all the precursor awards, the sag is probably the best indicator of the eventual Oscar winner. |
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In fish, the retrorse inclination of the myomeres forms a precursor of the differentiation between a deep and a superficial musculature of the trunk. |
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The circumstantial evidence all pointed towards cold as the precursor to death, but despite this the official inquiry gave drowning as the cause of death in every case. |
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Elijah Galloway patented Kamptulicon in 1843, a rubber and cork based floor covering that was a precursor to linoleum. |
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Glycocyamine is a direct precursor of creatine and is used as a supplement. |
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This precursor of the current North Sea has grown and shrunk with the rise and fall of the eustatic sea level during geologic time. |
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He believed its republican principles made it a precursor to the American Revolutionary War. |
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It is believed that in many ways this struggle was but a precursor to the American Revolution. |
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Its most important figure was David Cox, whose later works make him an important precursor of impressionism. |
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The first documents to show traces of what is today regarded as the precursor of modern Spanish are from the 9th century. |
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Rossetti came to be seen as a precursor of the wider European Symbolist movement. |
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His work also influenced the European Symbolists and was a major precursor of the Aesthetic movement. |
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Blake placed Edmund Spenser as Milton's precursor, and saw himself as Milton's poetical son. |
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His work is considered to be an early precursor of modern welfare economics. |
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The nonsense verse of Edward Lear, along with the novels and poems of Lewis Carroll, is regarded as a precursor of surrealism. |
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The precursor to variety shows of today, music hall involved a mixture of popular songs, comedy, speciality acts and variety entertainment. |
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A legacy of its two precursor bodies, the Authority's offices remain split over two sites, one in Glasgow and one in Dalkeith. |
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Minimalism is variously construed either as a precursor to postmodernism, or as a postmodern movement itself. |
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The Wealth of Nations was a precursor to the modern academic discipline of economics. |
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A precursor of the steam turbine, the steam wheel allowed the wheel to be directly turned by the pressure of the steam moving through it. |
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On 20 May 1926, Fighter Command's precursor organisation was established as a group within Inland Area. |
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The area was proposed as a National Park in 1965 by the National Parks Commission, a precursor body of the Countryside Commission. |
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It is often used for gravimetric analysis, exploiting the insolubility of the silver halides which it is a common precursor to. |
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In 1948 he published The Trials of Oscar Wilde, a precursor of three further books about Wilde. |
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West Francia approximated the area occupied by, and was the precursor, to modern France. |
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The earliest precursor of pollution generated by life forms would have been a natural function of their existence. |
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Wilson also noticed that the Atlantic had opened at roughly the same place where its precursor ocean had closed. |
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It does have a chondrified precursor and it assists the tendon in transmitting force. |
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Outside the United States the name was used in 1819 for the Gran Colombia, a precursor of the modern Republic of Colombia. |
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Progenitor cells such as the hematopoietic stem cell divide in a process called mitosis to produce precursor cells. |
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During the parade of nations Greece is always called first, as the founding nation of the ancient precursor of modern Olympics. |
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In Spain and Portugal this remains a separate tool, but elsewhere it was the precursor to the coulter. |
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The fort most likely lent its name to Koyil Kotta the precursor to Kozhikode. |
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Iranian cardiologist Tofigh Mussivand invented and developed the first artificial cardiac pump, the precursor of the artificial heart. |
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Criollo dissatisfaction resulted in the 1872 Cavite Mutiny that was a precursor to the Philippine Revolution. |
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The VOC is often considered as the precursor of modern corporations, if not the first truly modern corporation. |
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During World War I, Wilkinson Sword transitioned from mail to a lamellar design which was the precursor to the flak jacket. |
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The publication of Chaucer's work by William Caxton was a precursor to his publication of Malory's Le Morte D'Arthur. |
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It is a proposed basket of Asian currencies, similar to the European Currency Unit, which was the precursor of the Euro. |
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Since the ACU is being considered to be a precursor to a common currency in the future, it has a dynamic outlook of the region. |
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The American Enlightenment was a critical precursor of the American Revolution. |
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A precursor to modern commercial law, the Law Merchant emphasised the freedom of contract and alienability of property. |
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The oldest known archaeological fragments of the immediate precursor to modern paper, date to the 2nd century BCE in China. |
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Liquid phase sintering was successfully applied to improve grain growth of thin semiconductor layers from nanoparticle precursor films. |
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The principal use of aniline in the dye industry is as a precursor to indigo, the blue of blue jeans. |
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The diamines are condensed with phosgene to give methylene diphenyl diisocyanate, a precursor to urethane polymers. |
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Potholes form progressively from fatigue of the road surface which can lead to a precursor failure pattern known as crocodile cracking. |
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Then Argo swept the precursor awards and stole all its thunder. |
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Police searched the trucks and found two tons of acetic anhydride, an essential chemical precursor used for heroin conversion, hidden in bricks. |
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Thermal imidization of the amic acid precursor was achieved by first casting the poly solution onto pyrex glass plates. |
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Angola is not a major center of drug production, money laundering, or production of precursor chemicals, and is not likely to become one. |
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The technology creates precursor ions by way of ionization of air and then filtration through a primary quadrupole analyzer. |
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The short DNA fragment is the precursor of the newly synthesized DNA strand on the lagging strand. |
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Several melanocyte-stimulating hormones are normally produced along with ACTH via cleavage of the common precursor protein, proopiomelanocortin. |
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This can cause methaemoglobinaemia or act as precursor in the endogenous formation of carcinogenic nitrosamines. |
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For those not in the know, a monoski is the precursor to the snowboard, the prime differences being the stance and the use of poles. |
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Topograph, a software platform for precursor enrichment cor rected global protein turnover measurements. |
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These precursor lesions are detected with cervical cytology screening, the Pap smear. |
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Sugar beets contain a lot of the enzyme tyrosinase, which converts tyrosine into L-dopa, the precursor of dopamine. |
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Four molecules of this porphyrin precursor cyclize and undergo several side-chain modifications to yield the tetrapyrrole protoporphyrin. |
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Failure of infiltrating precursor cytotoxic T cells to acquire direct cytotoxic function in immunologically privileged sites. |
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It is the direct precursor to serotonin synthesis via the enzyme aromatic amino acid decarboxylase, which requires vitamin B6 as a cofactor. |
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Gevo has also patented a process by which isobutylene is dimerized to p-xylene, the petrochemical precursor to terephthalic acid. |
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The GSS is a precursor to the World Telecommunications Standardization Assembly, or WTSA, which will start today. |
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Byron is offered, not for the first time, as an important precursor of modern liberalism and homosocial politics. |
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Insulin is derived from a larger single chain precursor protein, proinsulin which contains 81 amino acids and three disulfide bonds. |
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The ORF encodes a precursor polyprotein that is proteolytically cleaved to form the functional protein products. |
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Psychotic traits include hallucinations and delusions, and can be a precursor to psychotic disorders. |
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The plant does, however, contain a compound called indican that is the dye's precursor. |
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As a result of organification, hormonally active iodothyronine, T4 and T3 precursor monoidotyrosines and diiodotyrosines occurs. |
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Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function. |
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These included predicted SERPINs, glycoprotein, pacifastin and serine collagenase 1 precursor. |
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Silicate gels were synthesized by hydrolyzing tetra functional alkoxide precursor, employing a mineral acid, HC1, as a catalyst. |
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Melanin is a heteropolymer of indole compounds that is produced inside melanosomes by the action of the tyrosinase enzyme on the tyrosinase precursor material in melanocytes. |
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In sporadic colon cancer, the dysplastic precursor is the tubular adenoma, a discrete focus of premalignant tissue often completely excised by endoscopic polypectomy. |
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Some observers have said Beijing's ADIZ over the East China Sea is a precursor to a similar zone over the South China Sea, which it claims almost in its entirety. |
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Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of antimalarial drug precursor, artemisinic acid. |
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As a result, precursor substitution reactions are often utilized to increase the length of these substituents in attempt to tailor the reaction kinetics. |
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The predicted precursor substitution reaction is shown in Fig. |
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For instance, a tree can convert the amino acid phenylalanine into cinnamic acid, a precursor to compounds thought to be important to the tree's defense system. |
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The orientation values for the precursor MDO films cooled under normal conditions and not stretched are very low, indicative of a spherulitic structure. |
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Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord. |
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In 2002, the Committee identified 25 substances as precursor chemicals, including two not in the 1988 UN Drug Convention and prohibited their import, sale or use in Burma. |
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A multi-billionaire, Niel began his business career at the age of 19 when he launched a sexual contact service on Minitel, France's dial-up precursor to the internet. |
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Following an extensive engineering design process, the baseline design concept for the South African MeerKAT precursor telescope has been decided. |
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Formation of the 67-kDa laminin receptor by acylation of the precursor. |
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Chemical companies supplying alkoxides and other precursor materials. |
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This may have been the precursor to beamworks in a number of locations, but enough lodeback pits survive to indicate that it was a separate technique. |
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Similar grants included land patents, which were land grants by early state governments in the USA, and printing patents, a precursor of modern copyright. |
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His attempts to form real socialist communities based on his ideas through the Icarian movement did not survive, but one such community was the precursor of Corning, Iowa. |
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This route, known as the Mangazeya seaway, after its eastern terminus, the trade depot of Mangazeya, was an early precursor to the Northern Sea Route. |
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Factories eventually spread to other parts of the world in the wake of European trading ventures and, in many cases, were precursor to colonial expansion. |
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Conversely, researchers have hypothesized that a precursor to syphilis may have been carried from the New World to Europe after Columbus's voyages. |
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Following the treaty of Verdun of 843, Alemannia became a province of the eastern kingdom of Louis the German, the precursor of the Holy Roman Empire. |
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Following the Treaty of Verdun of 843, Alamannia became a province of East Francia, the kingdom of Louis the German, the precursor of the Kingdom of Germany. |
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Drummond also introduced the show Mixing It which targeted the music genres that fell between Radios 1 and 3, often seen as a precursor to the programme Late Junction. |
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Billions of kilograms of chlorodifluoromethane are produced annually as precursor to tetrafluoroethylene, the monomer that is converted into Teflon. |
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In ancient times, the method of exhaustion was used in a similar way to find the area of the circle, and this method is now recognized as a precursor to integral calculus. |
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Its precursor was the 1976 Liberty Torch Run, a relay in which 33 runners marked America's bicentennial by covering 8,800 miles in 7 weeks through 50 states. |
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To finance the growing trade within the region, the Bank of Amsterdam was established in 1609, the precursor to, if not the first true central bank. |
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White silver nitrate, AgNO3, is a versatile precursor to many other silver compounds, especially the halides, and is much less sensitive to light. |
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This society would eventually become the precursor to the Royal and Ancient which is the governing body for golf everywhere outside of the United States and Mexico. |
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This colour scheme was the direct descendant of the colours worn by the precursor Aberdeen club, but lasted only one season before being replaced. |
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The earliest record of a recognised precursor to the modern game date from a match in County Meath in 1670, in which catching and kicking the ball was permitted. |
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His arguments were a precursor to the views of Mach and Einstein. |
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Complete nationalisation had been considered, and the Railways Act 1921 is sometimes considered as a precursor to that, but the concept was rejected. |
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It influenced the programmes and policies of major multilateral and bilateral development agencies, and was the precursor to the human development approach. |
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The European Economic Community was the precursor to the European Union. |
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This was a precursor to the following Christmas when two Challenge games were organised between the two sides but this time with one of each code. |
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Runciman noted that he had a romantic idea about the East, and the family decided that Blair should join the Imperial Police, the precursor of the Indian Police Service. |
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It is not known which, if any, of Chaucer's extant works prompted the reward, but the suggestion of him as poet to a king places him as a precursor to later poets laureate. |
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The modern mince pie's precursor was known by several names. |
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Parliament was not inherently progressive, with the events of 1640 a precursor for the Glorious Revolution, nor did Puritans necessarily ally themselves with Parliamentarians. |
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The tents served as a precursor for the permanent structured hospitals. |
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I see a precursor to Secretion in Todd Haynes's film Safe, in which Julianne Moore plays a woman who, like X, falls prey to an undiagnosable, untreatable wasting illness. |
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The exploration of unknown areas was often the precursor to colonization. |
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Achilles, although magnus, is configured as secondary in eminence to the emperor, as well as his heroic precursor in the form of the prelusory Achilleid. |
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Purines and pyrimidines serve as precursor molecules for DNA and RNA, as energy storage depots, as metabolic regulators, and as intermediates in biosynthetic pathways. |
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Both Dow and Solvay announced their intent to produce epichlorohydrin from glycerol, which in the past was the petrochemical precursor for glycerol. |
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