| The first separation is achieved by isoelectric focusing that separates protein polypeptide chains according to amino acid composition. |
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| One such intervention involves the intravenous injection of secretin, a gastrointestinal polypeptide. |
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| Almost 50 years ago, the author noted that the rotatory dispersion of unfolded polypeptide chains depends on the concentration of denaturants. |
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| The leader transcript contains an open reading frame which encodes a polypeptide of 44 amino acids. |
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| It is a basic protein with a single polypeptide chain and acts on cellular and model lipid membranes. |
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| There was no tumoral expression for serotonin, glucagon, insulin, gastrin, vasointestinal peptide, or pancreatic polypeptide. |
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| They both develop random transient beta-strands across the whole polypeptide chain. |
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| Possible modulators of growth include acetylcholine, dopamine, vasoactive intestinal polypeptide, and glucagon. |
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| The LDL receptor is a polypeptide of 839 amino acids that spans the plasma membrane. |
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| In recent years, it has become clear that the islets secrete several more hormones, including gastrin and pancreatic polypeptide. |
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| Vertebrate hemoglobins are tetrameric molecules comprised of two distinct polypeptide chains. |
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| Intranasal calcitonin is a polypeptide hormone that also inhibits osteoclastic activity. |
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| Protein synthesis inhibitors can rapidly block translation elongation and cause release of truncated polypeptide chains. |
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| Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin. |
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| The region indicated by the arrow is a sharp bend in the path of the polypeptide chain. |
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| In the Sec system, immature polypeptide chains are exported to the periplasmic space where they are folded into mature type. |
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| The thalassemias are another group of inherited disorders in which one or more of the polypeptide chains of globin are synthesized defectively. |
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| Prolactin-stimulating factors also exist, and included among them are GnRH, thyrotropin-releasing hormone, and vasoactive intestinal polypeptide. |
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| Thalassemia is caused by genetically determined abnormalities in the synthesis of one or more of the polypeptide chains of globin. |
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| The hormones capable of altering the MMC include insulin, pancreatic polypeptide, somatostatin, glucagon, secretin, motilin, gastrin, cholecystokinin, and neurotensin. |
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| They were focally positive for gastrin, somatostatin, and pancreatic polypeptide but tested negative for glucagon, serotonin, insulin, and inhibin. |
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| Venoms of the Elapidae snakes contain several postsynaptic polypeptide neurotoxins, such as bungarotoxin isolated from the venom of the banded krait. |
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| A polypeptide is cleaved into peptides by treatment with trypsin and cyanogen bromide, and the peptides are purified and sequenced. |
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| Many proteins contain 2 or more different polypeptide chains that are held in association by the same non-covalent forces that stabilize the tertiary structures of proteins. |
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| As well as the binding functionality provided by the biochemically-specific moieties they contain, the oligosaccharide might impart a steric stiffness to the polypeptide core. |
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| This process of bringing in corresponding amino acids builds the growing polypeptide chain. |
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| Trolamine polypeptide oleate, otherwise known as Cerumenex, is an over-the-counter product that comes with many warnings and side effects. |
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| An non human animal comprising an imaging marker trans gene, wherein said transgene encodes a cell surface polypeptide that binds an imaging radiolabeled hapten at high affinity. |
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| Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying. |
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| Multivalent molecular designs have emerged as an important tool for protein and polypeptide engineering complementary to the traditional methods of medicinal chemistry and recombinant antibody technology. |
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| By the process of limited proteolysis, in which several cuts in the polypeptide chains of these cofactors are formed by the enzyme thrombin, factors V and VIII are converted to active cofactors. |
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| Prolactin is a 198 amino acid polypeptide hormone, its principal physiological action is to initiate and sustain lactation. |
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| And finally, a recent development from the translational field is that a ribosome can manage to translate two different messenger RNAs into one single polypeptide. |
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| An antitumor active substance GIF characterized in that the substance GIF comprises as its component protein polypeptide A of the following primary structure and has the activity to inhibit the growth of tumor cells. |
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| The E Site is the exit site for the tRNA anticodon once it deposits its amino acid from the cytoplasm onto the growing polypeptide chain. |
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| Up until then, the explanation for antibody diversity had been based on the theory that one gene provides the recipe for one protein, or polypeptide chain. |
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| Vasoactive intestinal polypeptide stimulation of protein secretion from rat lacrimal gland acini. |
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| An apoprotein is a protein that has become detached from a second molecule that is not a polypeptide. |
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| A polypeptide fraction isolated from bacitracin and, on a weight basis, exhibiting at least 5 times the anti-insulinase activity of the bacitracin. |
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| Reductase nucleic acids and their encoded polypeptide were isolated and identified. |
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| An isolated single or double-stranded DNA molecule consisting of a nucleotide sequence which encodes a porcine adipocyte polypeptide leptin having the amino acid sequence of SEQ ID NO:4, or the complement to the DNA molecule. |
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| Microbiological Research Authority has patented a method of making a microparticle that contains DNA coding for a polypeptide. |
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| Coryneform bacteria in which the expression of a polyncleotide encoding a polypeptide having the amino acid sequence of SEQ ID NO: 2, wherein said polypeptide has the function of an efflux protein, is eliminated. |
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| A carrier protein-like polypeptide which comprises a sequence having an in-vivo effector activity of a polypeptide with the sequence of Fig. 4 and lacking the natural glycosylation of the carrier protein. |
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| A cell comprising a DNA sequence coding for at least the following elements fused sequentially into one open reading frame, a pectate lyase, a target site for proteolytic cleavage, and a polypeptide of exogenous origin. |
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| Prostaglandin action on the digestive tract may also cause severe watery diarrhea and may mediate the effects of vasoactive intestinal polypeptide in Verner-Morrison syndrome, as well as the effects of cholera toxin. |
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| An isolated and non-naturally occurring polypeptide having calmodulin-binding activity and actin-binding activity and comprising the amino acid sequence shown in SEQ ID No 1 in a polypeptide molecule. |
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| By 1959 Perutz had shown that the hemoglobin molecule is composed of four separate polypeptide chains that form a tetrameric structure, with four heme groups near the molecule's surface. |
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| Waldispuhl has already tested the model on a polypeptide called protein G, one of the few proteins for which information about the folding pathway is available. |
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| In this study, we found that pitrilysin, a zinc metallopeptidase of the inverzincin family, degrades monomeric, but not oligomeric, islet amyloid polypeptide in vitro. |
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| Their results revealed that subsets of neurons expressing thyrotropin-releasing hormone and pituitary adenylate cylcase-activating polypeptide were in on the neuronal chatter. |
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| Polypeptide neurotoxins act as competitive antagonists and include the venoms from snakes of the Elapidae and Hydrophidae families. |
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