| But recently, new forms of genomic variation have been appreciated above and beyond single nucleotide polymorphisms. |
|
| In the course of the study, we decided to include genetic polymorphisms of DNA repair genes. |
|
| Conditions for the selective maintenance of stable polymorphisms by antagonistic pleiotropy are quite restrictive. |
|
| Protein polymorphisms were detected using electrophoretic and isoelectric focusing methods modified from a variety of published sources. |
|
| Single nucleotide polymorphisms are stably inherited, highly abundant, and distributed throughout the genome. |
|
| Primary immunodeficiency diseases caused by genetic polymorphisms are now largely diagnosable with molecular probes. |
|
| The selective maintenance of inversion polymorphisms has been the subject of abundant theoretical work. |
|
| It would be useful to be able to screen individuals for gene polymorphisms that increase their stroke risk. |
|
| I had not worked on genetics since, as a Cambridge undergraduate, I had published juvenilia on polymorphisms maintained by single locus selection. |
|
| In some instances, genetic mutations or polymorphisms may underlie or contribute to these processes. |
|
| Detection of sequence variations, mutations and polymorphisms including identification of strains with increased resistance towards antibiotics. |
|
| These points are called single nucleotide polymorphisms, or SNPs, and there are 10m or so of them. |
|
| The first technique applied in forensics was the analysis of restriction fragment length polymorphisms. |
|
| Few investigations have been reported about the relationship between TLR9 polymorphisms and the tumor susceptivity. |
|
| Cetain genetic polymorphisms have been shown to be associated with infection in other medical conditions. |
|
| Microsomal epoxide hydrolase detoxifies reactive oxygen species generated by endotoxin exposure, and polymorphisms of the miH gene are associated with altered enzyme activity. |
|
| These polymorphisms have also led to identification through genetic fingerprints. |
|
| What's more, Celera is sequencing the genomes of six men and women of differing ethnic backgrounds to find single nucleotide polymorphisms. |
|
| Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. |
|
| All these polymorphisms are numbered relative to the adenine of the translation start codon. |
|
|
|
| Pneumocystis jiroveci dihydropteroate synthase polymorphisms confer resistance to sulfadoxine and sulfanilamide in Saccharomyces cerevisiae. |
|
| Ontogenic expression pattern and genetic polymorphisms of the fatty acid transport protein 4 gene in Chinese chicken populations. |
|
| Moreover, genetic polymorphisms for glutathione-S-transferases and epoxide hydrolase might also contribute to considerable variation in sensitivity. |
|
| Many polymorphisms of the ADRB I gene were studied before, but 13 of them were found to change the amino acids of the ADRBI protein. |
|
| An interesting point is that there are many possible genetic polymorphisms that can relate to diabetes mellitus. |
|
| Marker polymorphisms were used to determine the allelic origin of lactase mRNA transcripts. |
|
| In addition, these three genes have been shown to have functional polymorphisms that are frequently present in the general population. |
|
| An assay based on PrASE was set up for screening of the MC1R and CDKN2A polymorphisms suggested to be present in the Swedish population. |
|
| However, the abundance of SNPs and progress in SNP genotyping technology will eventually ensure that forensic systems evolve to incorporate these polymorphisms. |
|
| Sequence variations, mutations and polymorphisms can be detected by simultaneous hybridization analysis of a target DNA molecule with a very large number of probes. |
|
| Recent work has explored the risk associated with common genetic polymorphisms and their relationships with both folate and vitamin B12 status and NTD risk. |
|
| Complicated factors can arise due to the presence of genetic polymorphisms in ancestral species and resultant lineage sorting. |
|
| Insertion polymorphisms of SINE200 retrotransposons within speciation islands of Anopheles gambiae molecular forms. |
|
| Is transient tachypnoea of the newborn associated with polymorphisms in the epithelial sodium channel encoding gene? |
|
| Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan. |
|
| A number of thrombophilic gene polymorphisms that are suspected to associate with RPL, have been reported. |
|
| Preexisting factors such as genetic polymorphisms may play an important role. |
|
| The most common human sequence variations are differences in individual base pairs, termed single nucleotide polymorphisms. |
|
| The major drawback of this technique, however, is that informative short tandem repeat polymorphisms found to be optimal in one human population maybe ineffective in another. |
|
| Scarce data exist concerning CRP polymorphisms in diabetic patients. |
|
|
|
| However, there is no report describing polymorphisms of GnRHR gene in teleosts, and few studies about the relationship between mutants and reproductive traits. |
|
| The evolution and function of stylar polymorphisms in flowering plants. |
|
| According to recent genetic analysis, both mtDNA and Y chromosome polymorphisms showed a noticeable genetic affinity between Swedes and other Germanic ethnic groups. |
|
| However, little is known about the genotoxicity of pesticides in people with various genetic polymorphisms of human xenobiotic metabolizing enzymes coding genes. |
|
| Several specialized databases exist that report polymorphisms and mutations in the human mitochondrial DNA, together with the assessment of their pathogenicity. |
|
| Moreover, trans effects of single-nucleotide polymorphisms that affect TPMT activity and mercaptopurine sensitivity have recently been discovered in the PACSIN2 gene. |
|
| Polymorphisms produced by the remaining three probes all failed to map to the expected location and were suffixed with like1, like2, etc. |
|
| Polymorphisms on chromosomes 5, 6 and 15 are known to affect the risk of lung cancer. |
|
| Polymorphisms in the beta2 adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers. |
|
| Exonic regions of BOP gene were amplified by polymerase chain reaction and amplified exonic regions were analyzed by Single-Strand Conformation Polymorphisms. |
|
