It was noted that even within a class of chemicals such as peroxisome proliferators, individual chemicals had differing target organs and mechanisms of toxicity. |
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The glycosome is related to the peroxisome, a nearly ubiquitous eukaryotic organelle. |
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There are several types, by far the most common of which is the peroxisome. |
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Liver peroxisome proliferation was significantly elevated only in the high-dose group after 26 weeks, but not at 52 weeks. |
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It was concluded that peroxisome proliferation is not necessarily linked to tumour production under the conditions of this subchronic study. |
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In contrast, hepatic hypotriglyceridaemia is of relevance to humans, because the hypolipidaemic effect of peroxisome proliferators is common to both experimental animals and humans. |
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In an initiation-selection-promotion protocol for induction of liver tumours, five peroxisome proliferators including 2,4-D were tested for their promoting and modulating action in hepatocarcinogenesis. |
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Ligand-independent activation domain in the N terminus of peroxisome proliferators-activated receptory. |
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The plant glyoxysome is a peroxisome that also contains the enzymes of the glyoxylate cycle, which is crucial to the conversion of fat into carbohydrate. |
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They upregulate peroxisome proliferator-activated receptor-alpha, which increases fatty acid oxidation from peroxisomes and mitochondria. |
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No evidence of peroxisome proliferation in the liver was reported. |
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The two proteins added today are phosphodiesterase IV and peroxisome proliferator-activated receptor delta, both are active targets of structure based drug design. |
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Ibuprofen's protective effect may be due to the drug targeting a brain protein called the peroxisome proliferator-activated receptory, said the researchers. |
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Peroxisome Proliferator Activated Receptor gamma is the key regulator of the immune and inflammatory response. |
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