How to use pepsin in a sentence

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Sentence Examples The 14 specimens positive for pepsin strongly suggest that aspiration of gastric juice occurred in 5 of the 30 high-risk patients in the study. We do not know the length of time after a single aspiration of gastric juice that pepsin can be detected with this immunoassay. It also stimulates release of bile from the liver and pepsin from the stomach. In the stomach, pepsinogen is secreted, and activated into pepsin by the acid that is secreted at the same site. It produces excessive gastrin, resulting in disproportionate amounts of hydrochloric acid and pepsin leading to severe peptic ulcer disease. Enzyme predigestion with pepsin was performed as recommended by the manufacturer. Many people take extra doses of naturally produced enzymes, such as lactase, pepsin and trypsin, in supplement form. All 10 of the gastric specimens tested positive for pepsin, and all 10 of the tracheal specimens were negative. The gastric enzyme, pepsin, along with hydrochloric acid, help break proteins into smaller units called peptones. Such damage results from the low pH of stomach acids working in conjunction with the digestive enzyme pepsin. The chief cells secrete pepsinogen, which is converted to the active enzyme pepsin by hydrochloric acid secreted by the parietal cells. The pepsin or pancreatin shall be added to the respective stock solution in the proper quantity just before use. Here we report on the opsonic potential of the resulting sera and the level of protection induced by this peptide in comparison to a pepsin extract of the M protein. Coagulation: this is induced using rennet, the active components of which are the enzymes chymosin and pepsin. This barrier protects the ulcer site from the potential ulcerogenic properties of acid, pepsin and bile. Furthermore, sucralfate blocks acid diffusion across the sucralfate protein barrier and also complexes directly with pepsin and bile. For pools of up to 50 g, the digestion fluid and the ingredients may be reduced to 1 litre of water, 8 ml of hydrochloric acid and 5 g of pepsin. Although the pepsin resistance protocol is strongly recommended, it is recognized that other enzyme susceptibility protocols exist. Available information, however, supports a central role for H. pylori and a necessary role for acid and pepsin. A peptic ulcer is a nonmalignant, mucosal lesion of the stomach or duodenum in which acid and pepsin play major pathogenic roles. Show More Sentences Rennet contains, in fact, two enzymes: chymosin as principal constituent, and pepsin. In animals that lack rennin, milk is coagulated by the action of pepsin as is the case in humans. In the stomach, protein materials are attacked initially by a gastric endopeptidase known as pepsin. Proteins in food are attacked in the stomach by pepsin and in the small intestine mainly by trypsin and chymotrypsin from the pancreas. Sunflower protein hydrolysate is obtained through hydrolysis using pepsin and pancreatin. Esophagitis is a complication of reflux and it develops when the mucosal defenses that normally counteract the effect of injurious agents on the esophageal mucosa succumb to the refluxed acid pepsin or bile. Sulfated polysaccharide has been known for a long time to possess an inhibitory action on proteolytic activity of pepsin and a preventive action on experimental peptic ulcerations. Long and extended, complex structure, few acidic salts and pepsin. Results of in vivo and in vitro studies show that sucralfate produced an adherent and cytoprotective barrier at the ulcer site which resisted degradation by acid and pepsin. In 1836, while investigating digestive processes, he isolated a substance responsible for digestion in the stomach and named it pepsin, the first enzyme prepared from animal tissue. Hydrochloric acid and pepsin, adequate amounts of which are necessary for satisfactory digestion, are produced by the stomach in decreased amounts during pregnancy. I think it's a bit shortsighted to blame pepsin because you're not selectively refluxing pepsin. The reference method laid down in Annex I to that Regulation requires that for the detection of Trichinella larvae in meat samples, 10 ± 0,2 g of pepsin is to be added to the sample. Use the graduated cylinders to measure the pepsin and HCl solutions into the bags. The authors highlight this versatility by targeting the C-terminal fragment peptide to provide a combined measurement of pepsin and pepsinogen. Its low pH denatures proteins and thereby makes them susceptible to degradation by digestive enzymes such as pepsin. In a clinical study, sucralfate was administered to ulcer patients and the effects on pepsin activity was monitored for 30 minutes after ingestion of the drug. It accomplishes this phenomenon by activating a chemical reaction that serves as an antiacid buffer while suppressing the secretion of pepsin, a protein-digesting enzyme produced in the stomach. Examples from Classical Literature The pepsin is added to the mixture only when warm, and is injected at once. The use of pepsin for this purpose cannot serve nature's purpose, as it contains neither sodium carbonate nor sodium sulphate. The pepsin of the gastric juice and the trypsin of the pancreas split the native proteins only to peptones. The chief distinction is that trypsin acts in an alkaline solution, while pepsin acts in an acid solution. They have some sort of pepsin which comes out of their mouths and does this work. It had sounded just like pepsin, and he didn't believe there was such a word. Its function is to convert the proteids into peptone, which is effected by its active principle, termed pepsin. I have a bottle of pepsin that comes from the School of Chemistry at Montpellier. Why does pepsin act only on proteid matter, and ptyalin only on starch and dextrins? Its chief constituents are two ferments called pepsin and rennin, free hydrochloric acid, mineral salts, and 95 per cent of water. A demonstration of tryptic activity in a mixture containing both pepsin and pancreatin is of merely theoretical interest. Deficiency of rennin has the same significance as deficiency of pepsin, and is more easily recognized. Since the two enzyms are almost invariably present or absent together, the test for rennin serves also as a test for pepsin. Luciferase is destroyed only by pepsin, trypsin, erepsin, and something in spleen and liver extract. Control feedings with an emulsion of one-half gram each of pepsin and pancreatin proved inactive. Secretion of pepsin and rennin is always diminished in marked cases. The reason is the failure of the pepsin to act on epidermic substances. These unorganized ferments are such as rennin, pepsin, trypsin, ptyalin. Activities to be measured is pepsin in gastric juice, trypsin and total proteolytic activity in intestinal juice. In contrast, pepsin activity in the gastric juice of starved animals was the greatest. Show More Sentences However, the TA had no significant effects on gastric mucus secretion and pepsin activity. Also the Old Boarder who was always under the influence of pepsin. Now, I am going to add a pinch of pepsin to the contents in these tubes. This is a substance distinct from pepsin, but its action is the same. I had to give him five pepsin lozengers and some pepper tea. Between blasts she resorted to Epictetian philosophy in the form of pepsin chewing gum. Find more words! 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Use our Sentence Generator Nearby Words Pepsi peps peppy pepping peppiness peppily pepsinogen pep talk peptic peptidase peptide peptide bond 6-letter Words Starting With p pe pep peps pepsi