| Indeed, if sequence divergence decreases hybridization signal, these genes should have more frequently appeared overexpressed than unexpressed. |
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| A protooncogene only becomes oncogenic when it is overexpressed or when its sequence is mutated. |
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| Similarly, other genes may be overexpressed in cases of uniparental disomy, perhaps also leading to clinical complications. |
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| In those with alopecia, it seems, this gene is greatly overexpressed in hair follicles, leading to rapid hair loss. |
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| Both enzymes were successfully overexpressed in Escherichia coli and their activity and substrate specificity were studied. |
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| Then we made mice that overexpressed this transcription factor at slightly higher than normal levels. |
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| This study led to defning of 5 overexpressed genes in patients with UC who were non-responders to infliximab. |
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| These genes may be overexpressed and underexpressed with respect to the other genes and with respect to a particular condition. |
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| A method for increasing secretion of an overexpressed gene product from a host cell which comprises effecting the overexpression of at least one hsp70 chaperone protein. |
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| Both gastrin and the CCK-B receptor are overexpressed in pancreatic cancer. |
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| This led to the definition of a sub-population, consisting of patients in whom CK2 was both overexpressed and abnormally relocated in the nuclear compartment of cancer cells. |
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| Molecules known as E-cadherin, which changes cell-to-cell adhesion in epithelium, and N-cadherin, which favours cell migration, have been found to be under expressed and overexpressed in invading cancer cells. |
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| But it also turned out to inhibit another kinase receptor called c-kit, which is overexpressed in gastrointestinal stromal cancer, as well as abl, the internal kinase whose gene goes awry in chronic myelogenous leukemia. |
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| Indeed, in order to establish the link between a gene and its function, researchers need to observe the differences depending on whether the gene being studied is activated or overexpressed. |
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