| Any patient with suspected myxedema coma should be treated presumptively with thyroid hormone. |
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| The presence of goiter, coarse hair, dry skin, carotenemia, and myxedema indicates hypothyroidism. |
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| The differential diagnosis includes venous stasis dermatitis, pretibial myxedema, filariasis, and ichthyosis. |
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| A common misconception is that a patient must be comatose to be diagnosed with myxedema coma. |
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| Patients with myxedema present with rough skin of the palms, soles, elbows and knees, and yellow-orange discoloration of the skin, along with other signs of hypothyroidism. |
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| Nearly all patients with localized myxedema have had hyperthyroidism in the past and have severe ophthalmopathy. |
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| Under such circumstances, intravenous therapy should not be undertaken without weighing the alternate risks of myxedema coma and the cardiovascular disease. |
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| Uric-acid salts are deposited in gout, calcium salts in calcinosis, lipids in xanthomatosis, an abnormal protein in amyloidosis, mucin in myxedema, and porphyrins in porphyria. |
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| Enhanced susceptibility to iodine myxedema in patients with Hashimoto's disease. |
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| Induction of myxedema by iodide in patients euthyroid after radioiodine or surgical treatment of diffuse toxic goiter. |
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| William Osler described the syndrome in 1898 but he wrongfully attributed it to myxedema. |
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| Scientific literature on coexistance of myxedema coma and NMS is sparse. |
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| Our patient's hospital stay spanned almost 3 months, most of which was in the intensive care unit, and she suffered several complications of myxedema coma. |
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