| Four of the eight QTL for reduced homozygous seed set are colocated with QTL associated with reduced male fertility. |
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| To simplify the analysis, mate the dihybrid with a homozygous recessive strain. |
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| The double dagger on chromosome 6 indicates the region that is preferentially homozygous W22 in both mutant and wild-type kernels. |
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| In incomplete dominance, a heterozygote's phenotype will be intermediate between the two possible homozygous phenotypes. |
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| One young insertion was found to be homozygous in two wild-type strains and absent in six others. |
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| Transformants were induced to sporulate and the resulting tetrads were dissected to generate homozygous deletions. |
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| The alb1 mutation is recessive and homozygous albino plants are white and die at the seedling stage. |
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| Therefore, continuous supply of recombinase would promote the generation of homozygous cells. |
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| Analysis of homozygous germline clones can be employed to reveal the role of pleiotropic genes in pole plasm formation. |
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| Testing of two PRA affected animals within a 17th breed, the bull mastiff, revealed one heterozygote and one homozygous normal animal. |
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| Separation of the chromatids at mitosis produced one daughter cell homozygous for the chromosome arm carrying an EMS-induced mutation. |
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| Flies homozygous for such hypomorphic mutations reach adulthood, but often exhibit defects during the proliferative stages of gametogenesis. |
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| The program was successful at Paint of a Different Color the first year and Al ended up with a beautiful homozygous filly and a palomino paint colt. |
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| However, to a low extent, viable spores can also be recovered from a very small population of homozygous diploid nuclei in an otherwise haploid plasmodium. |
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| In patients homozygous for the G1m17,1 allotype, infliximab is in competition with endogenous IgG with the G1m17,1 allotype. |
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| A mutagenesis strategy autocatalytically converts mutations to the homozygous condition in fly somatic and germline cells. |
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| The inbreeding coefficient is a measure of the proportion of loci that are homozygous because of the relationship between the parents. |
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| There's no healthy mating scheme with such a dominant trait, no matter whether the cat is heterozygous or homozygous. |
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| In addition, ANF or NPRA gene disruption leads to salt-sensitive or salt-insensitive hypertension, respectively, in homozygous null mice. |
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| This is the case at present for idiopathic hemochromatosis since it is possible to give preventive treatment to homozygous children. |
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| Females can be either homozygous or heterozygous for sex-linked traits because they have two X chromosomes and therefore two alleles of every sex-linked gene. |
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| The homozygous sickle-cell condition is responsible for the deadly effects of sickle-cell anemia, whereas the heterozygous condition is usually asymptomatic. |
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| Plumage color of homozygous birds varies from slaty blue to beige depending on the relative abundance of eumelanin and pheomelanin in the feathers. |
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| Patients with antithrombin deficiency or homozygous FVL need life long anticoagulation after a first VTE event due to high recurrence risk. |
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| Genome-engineered cells homozygous for these mutations have largely normal centriole numbers but show reduced CEP120 levels, compromised recruitment of distal centriole markers, and deficient cilia formation. |
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| Second, you have to inbreed incredibly strongly in order to get all or almost all loci homozygous, so that you can see what the cats are carrying and weed out all the undesirable genes. |
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| We report 3 cases with 1 homozygous and 2 heterozygous mutations at codon 37 causing a premature stop codon. |
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| This means that for a given gene, consanguineous offspring are more frequently homozygous than others. |
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| Peloric individuals are homozygous recessive for the cyc308G allele with both copies being hypermethylated and completely silenced for RNA expression. |
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| To check that standard curves were generated with truly homozygous individuals four of them were sequenced for three SNPs confirming the homozygosis. |
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| The spontaneous mutant mouse staggerer, with an ataxic gait caused by neurodegeneration of cerebellar Purkinje cells, was discovered two decades ago to result from homozygous intragenic Rora deletions. |
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| When any one of the two or both the genes are present in the homozygous recessive state, the contrasting phenotype is produced, which leads to various modifications of the typical dihybrid, trihybrid etc. F2 ratio. |
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| When two mutations occur in different genes, they are said to be complementary, because the heterozygote condition rescues the function otherwise lost in the homozygous recessive state. |
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| We utilize the FLP-FRT technology to generate and select for homozygous mutant germline clones within heterozygotes. |
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| In the course of this work the scientists discovered a new homozygous recessive form of the disease associated with mutations in exon 12 of the gene encoding elastin in three patients from two related Syrian families. |
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| A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. |
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| If a duplication becomes homozygous, it can provide the organism with an opportunity to acquire new genetic functions through mutations within the duplicate copy. |
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| When the alleles for a given trait are identical, the organism is said to be homozygous with respect to that gene, and the appearance of the corresponding trait is assured. |
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| When an animal receives the same allele from both parents it is said to be homozygous for that gene while animals with different alleles of a gene are considered heterozygous. |
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| If it seems logical to use genetics to prevent birth of homozygous affected by disease, it would make no sense to eliminate the bad genes altogether. |
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| Also, the immune system is not very good in homozygous individuals. |
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| Thus the gene which produced atavistic digits in the vigorous heterozygous pentadactyl condition is a lethal monster in the homozygous condition. |
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| Of these 28 patients, 24 were homozygous and heterozygous secretors and 4 were nonsecretors. |
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| Seeds homozygous for ser1 were mutagenized with EMS, germinated and grown to maturity. |
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| After the initial discovery, the mutants were crossed inter se and pure homozygous stock of the mutant was established. |
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| Fgfr1 null mutant embryos die during gastrulation and segmentation, while homozygous embryos of Fgfr2 knockout die before gonad formation. |
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| When, by chance, both parents pass on the same allele for a particular gene, their child is homozygous for that allele, meaning she has two identical copies of the allele. |
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| An 8-year-old girl with homozygous sickle cell disease had been receiving monthly transfusions and chelation therapy since having a stroke 3 years earlier. |
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| The homozygous, recessive hereditary erythroblastic anemia mouse is characterized by a hypochromic, microcytic anemia that is lethal 5-7 days after birth. |
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| Preliminary studies have shown that the mountain gorilla population is relatively homozygous at the MHC loci when compared to humans, and this lack. |
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| However, the appearance of homozygous forms without consanguinity and coincidence of two types of porphyria in the same patient, dual porphyrias, is possible. |
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| In nature, this mode of reproduction can yield highly homozygous lines composed of individuals so genetically uniform as to be, in effect, identical to one another. |
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| The frequency is one in five hundred for heterozygous familial hypercholesterolemia and one in a million that are homozygous famililal hypercholesterolemia. |
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| Homozygous phenotypes of the recombinant lines were analyzed. |
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| Homozygous mutants were obtained by intercrosses of the heterozygotes. |
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