| These observations add further support for a lack of thrombogenicity with heterozygous plasminogen deficiency. |
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| Maybe you assumed that the dominant allele would always be expressed in a heterozygous individual. |
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| Animals developed as perfectly normal hermaphrodites if derived from a heterozygous hermaphrodite mother. |
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| Individuals with normal and heterozygous genotypes are both infected by falciparum that causes malaria fever. |
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| If a mother is heterozygous for a particular sex-linked gene, her son has a 50% chance of inheriting either allele from her. |
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| Amplification with both normal and mutant primers indicates the heterozygous deletion of that type. |
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| We sequenced genomic DNA from heterozygous animals in an attempt to identify the remaining mutations. |
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| In practice this model could be extended to include inferences from crosses with resulting heterozygous individuals, such as backcrosses or intercrosses. |
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| In addition, researchers studied persons with diabetes, obesity, individuals heterozygous for phenylketonuria, and lactating women. |
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| This method magnifies the effect of heterozygous mutations on the posterior phenotypes, thus identifying even lethal genes involved in the targeted process. |
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| Females can be either homozygous or heterozygous for sex-linked traits because they have two X chromosomes and therefore two alleles of every sex-linked gene. |
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| There's no healthy mating scheme with such a dominant trait, no matter whether the cat is heterozygous or homozygous. |
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| In this case, one haploid M. graminicola isolate would become heterozygous disomic for that chromosome. |
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| A heterozygous individual has a 50 percent chance of passing the disorder to his offspring. |
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| However, individuals who are heterozygous for inversions produce aberrant meiotic products along with normal products. |
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| The homozygous sickle-cell condition is responsible for the deadly effects of sickle-cell anemia, whereas the heterozygous condition is usually asymptomatic. |
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| In a diploid a heterozygous deletion results in a cell that has one normal chromosome set and another set that contains a truncated chromosome. |
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| Ten wild-type females crossed with mutant males gave birth to 22 heterozygous mutant mouse pups and 30 wild-type littermates, which were used as control pups. |
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| All families harbored compound heterozygous mutations, most commonly a truncating mutation combined with a missense mutation. |
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| In a 6-month carcinogenicity bioassay in heterozygous p53 knock-out mice, there were no neoplasms or other proliferative lesions attributable to the administration of eplerenone. |
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| Figure 3E shows an example of metaphase spread and its karyogram of a heterozygous diploid. |
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| We report 3 cases with 1 homozygous and 2 heterozygous mutations at codon 37 causing a premature stop codon. |
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| In the group of orally infected squirrel monkeys, 3 had a unique heterozygous genotype that encoded either 4 or 5 octapeptide repeats. |
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| The method would therefore be amenable to screening an X-linked dominant disorder with heterozygous females and hemizygous male patients. |
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| The heterozygous females in these lines ended up laying about 10 percent more eggs than flies that had no Indy alleles with Hoppel. |
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| Sequencing analysis of the intergenic region between CYP2D8P and CYP2D7P revealed that the individual was heterozygous at several positions. |
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| When an animal receives the same allele from both parents it is said to be homozygous for that gene while animals with different alleles of a gene are considered heterozygous. |
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| A cell bearing a heterozygous translocation has a full set of genes and will be viable unless one of the breaks causes damage within a gene or if there is a position effect on gene function. |
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| The immune system works much better if the loci involved are heterozygous, since this gives the individual the possibility to develop more DIFFERENT kinds of antibodies, not just lots of antibodies of the SAME kind. |
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| Finally, the gene for ataxia telangiectasia, recently identified, could also in the heterozygous state, be an important gene for susceptibility to various cancers, inter alia breast cancers. |
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| If the screened newborn is indeed heterozygous, a great deal of effort will be needed to avoid causing parents excessive anxiety, which will add significantly to the genetic counselling burden. |
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| Thus the gene which produced atavistic digits in the vigorous heterozygous pentadactyl condition is a lethal monster in the homozygous condition. |
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| Of these 28 patients, 24 were homozygous and heterozygous secretors and 4 were nonsecretors. |
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| Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma. |
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| Evaluation of thrombophilia disorders established the patient to be heterozygous for methylenetetrahydrofolatereductase C677T gene mutation as the only finding. |
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| DeNovoMAGIC proprietary algorithms enable the full mapping of even the most large and complex genomes, including heterozygous and polyploidy genomes. |
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| The Indian people who came to Natal originated in regions where malaria was endemic, and many were heterozygous for a thalassaemia trait that protected them from malaria. |
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| Karyotyping is superior at detecting low-level mosaicism, some ploidies, balanced but potentially pathogenic rearrangements, and de-novo heterozygous pathogenic mutations. |
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| The frequency is one in five hundred for heterozygous familial hypercholesterolemia and one in a million that are homozygous famililal hypercholesterolemia. |
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| Thus, duplication mutations in affected boys, and duplication or deletion mutations in heterozygous females cannot be identified using this technique. |
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| Since the whippets that win races are usually the ones breeders select to pass on their genes, it is not unusual for two heterozygous dogs to be mated. |
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| Heterozygous hypobetalipoproteinaemia results in low LDL concentrations, but these subjects have a postprandial increase in plasma triglyceride concentration. |
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