How to use heparin in a sentence

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Sentence Examples Open the clamp and irrigate with heparin, clamping the catheter as the last of heparin is instilled. Coumarin drugs, such as warfarin as well as the glycosaminoglycans, heparin and heparan sulfate, are useful as anticoagulants. Heparin-induced thrombocytopenia is uncommon with the use of porcine heparin and is less common with low-molecular-weight heparin. Two other glycosaminoglycans, namely heparin and chondroitin sulfate B, were also studied with isothermal titration calorimetry. Another supplement that may prolong bleeding is phosphatidylserine, which synergistically stimulates the effects of heparin. In some cases, doctors may recommend low doses of aspirin along with heparin. This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin. The abnormal variant in both cases bound heparin normally but failed to bind dermatan sulfate as demonstrated by crossed immunoelectrophoresis. In intraoperative cell salvage all shed blood is suctioned to a storage system, and heparin is added to prevent thrombus formation. This effect of heparin is the basis for its clinical use as an anticoagulant. This clearly suggests that the newly formed species may correspond to complexes of PEI with heparin. Some antibiotics, such as gentamicin, penicillin G, tetracycline, methicillin, erythromycin, and vancomycin, are not compatible with heparin. But in the real life scenario, the predicted advantages of heparin coating don't seem to feature. Patients receive heparin in many ways, including heparin line flushes, subcutaneous heparin, and heparin-coated indwelling catheters. Blood was collected from untreated albino mice using heparin as the anticoagulant. They have tried to deal with coagulation by coating a device with heparin or a heparin-like substance. The patient was started on heparin, and a percutaneous, ultrasound-guided needle core biopsy of the retroperitoneal mass was performed. There is no evidence that anticoagulation with either heparin or warfarin improves these outcomes. It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin. The morning after he's dialyzed, while still on subcutaneous heparin, he tells an alert resident about slight breathlessness. Show More Sentences In one set of experiments, they loaded the sugar dextran, the anticoagulant heparin, or a growth hormone into reservoirs on separate chips. This product is approved for more clinical indications than any other low-molecular-weight heparin. Examples of anticoagulants include aspirin, heparin, and warfarin. If heparin is used, brain imaging should be performed prior to initiation of therapy to exclude hemorrhage and estimate infarct size. This interaction is used clinically to antagonize the anticoagulant effect of heparin. Recent reports indicate that osteoporosis may be reversible after discontinuation of heparin. Patients with a history of deep vein thrombosis or thrombophlebitis who have surgery should receive perioperative subcutaneous heparin prophylaxis. Hematologic: Bleeding is the most common side effect of heparin and is an extension of its pharmacological effect. Withdraw the needle quickly and apply alcohol swab pressure to the site of injection for 5-10 seconds to prevent loss of the heparin. After recanalization, heparin and DAPT were restarted, and bleeding occurred. She administers heparin through the cath and then draws some blood through it for testing. Anticoagulation for a woman unable to take heparin, for whatever reason, should be managed by a haematologist. For ex­ample, DIC requires immediate intervention with heparin, platelets, and whole blood to prevent exsanguination. It is known that endogenous KGF is a heparin binding protein, therefore, it binds to heparin sulfate proteoglycans. Any excess protamine sulfate, not complexed to heparin, has its own intrinsic anticoagulant effect. The osteoporotic effect is felt to be reversible within several months upon discontinuation of heparin. In some cases, the emergence of firm nodules which do not indicate an encystment of the heparin may be noted. In some cases, the emergence of firm nodules, which do not indicate an encasement of the heparin, may be noted. Limited data suggest that dextran and heparin may act synergistically when administered concurrently. A dosing ratio of 1 milligram protamine for every 100 units of heparin remaining in the patient is the usual rule. Show More Sentences Postoperatively low molecular weight heparin and lymphatic drainage are important in the patient's postoperative management. Postoperatively, each of the three ports of the CVAD was flushed three times a day with heparin flush solution. A substance as toxic as heparin, a rat poison, turns out to be an effective anticoagulant which has saved many lives. In the heparin case Chinese suppliers replaced the main ingredient with a cheaper, dangerous substance that still passed authentication tests. Anticlotting medical plastics have been prepared containing sulfonated polymers that bind heparin, a natural polysulfate. Allowance should be made for the rapid removal of heparin from circulation. It may be applied alone or in combination with sutures, even in patients being treated with heparin and in hypothermia. This has been reported both with unfractionated heparin and with low molecular weight heparins. The company BIOIBÉRICA, SA is devoted to the manufacture of pharmaceutical products, condroitin sulphate and heparin, among others. In the event of serious bleeding, heparin and antiplatelet agents should be discontinued immediately. In 2008, the drug heparin was tied to dozens of deaths after most of the active ingredient was swapped with a counterfeit. We took blood from the alar vein in the wing by inserting a needle into the vein and drawing blood into a vacutainer containing the anticoagulant lithium heparin. Blood thinners, or anticoagulants, such as heparin, will not dissolve clots already formed, but will keep them from growing and prevent new ones from forming. Additionally, low molecular weight heparin was used in only about 56 percent of patients with blood clots in the legs or phlebitis, an inflammation of the vessels in the legs. Heparin-induced thrombocytopenia is an immune-mediated complication of heparin administration that contraindicates further heparin exposure. The biological activity of heparin depends on the presence of antithrombin III, a substance in blood plasma that binds and deactivates serum clotting factors. As erythropoietin and heparin attest, the study of sugars, a field known as glycobiology, can be big business. There is insufficient evidence to date to suggest that LMWH is superior to unfractionated heparin in the prophylaxis and treatment of VTE in obstetrics. A multicentre randomised study of warfarin or heparin after a Fontan procedure was reported. Use of a modified human heparin cofactor II wherein the leucine residue at position 444 is replaced by arginine, for the manufacture of a medicament for use in human antithrombotic methods. Show More Sentences A complex chain of sugar molecules extracted from pig intestine, heparin binds to antithrombin, heightening the protein's ability to mop up the enzyme thrombin, which normally kick starts coagulation. Additional doses of protamine sulfate should be administered if indicated by coagulation studies, such as the heparin titration test with protamine and the determination of plasma thrombin time. These antibodies are found in some patients undergoing heparin therapy. He had no history of previous heparin exposure, and no heparin was given preoperatively or intraoperatively. Apparent resistance to heparin may be encountered in patients with acquired or familial AT III deficiency, because adequate levels of AT III are required for heparin's anticoagulant effect. Heparinised plasma is the virtually cell-free supernatant following centrifugation of whole blood, the coagulability of which is inhibited by the addition of heparin immediately after blood collection. He was given a bolus injection of heparin intraoperatively and an intravenous infusion of heparin preoperatively and postoperatively. The most frequently used treatment options are surgical embolectomy, thrombolytic therapy, and heparin. Comparative inactivation of isepamicin, amikacin, and gentamicin by nine beta-lactam and two beta-lactamase inhibitors, cilastatin and heparin. Although mortality of thrombolysis and heparin was same as previous report in Rose series, mortality of pulmonary embolectomy was high. The researchers gave a sixth group of patients injections of enoxaparin, a derivative of heparin. The physician should weigh the potential risks with the potential benefits to the patient in determining whether to administer a low molecular weight heparin in this patient population. On day 11, argatroban was initiated in lieu of heparin, however, the patient died on day 14 from initial exposure to heparin. The management of pulmonary embolism is initially conservative, using either intravenous unfractionated heparin or low-molecular-weight heparin. An intern underdosed her heparin, and she suffered a large blood clot in a lung. The potential utility of this model in the identification of new inhibitors of amyloid formation will be tested using low molecular weight heparin mimetics that have already shown promise as anti-amyloid drug candidates. Most commercial heparin is obtained from cow lungs or pig intestines. Heparin Sodium Injection, USP is a sterile, non-pyrogenic solution of a highly purified sodium salt of heparin, a high molecular weight polysaccharide derived from porcine intestinal mucosa or beef lung. As a result, unfractionated heparin is poorly bioavailable and has variable clearance and elimination due to plasma protein and endothelium binding. Likewise, when nitroglycerin therapy is stopped, a decrease in heparin dosage may be necessary and patients should be monitored for signs of excessive anticoagulation. Show More Sentences An extra modification step occurs in heparin and heparan sulfate by the deacetylation and N-sulfation of GlcNAc residues. The drugs that will become cheaper would include atorvastatin, gliclazide, glimepiride, heparin and metolazone among others. This medicine is a lowmolecular-weight heparin marketed by Sanofi-aventis and used for the prevention and treatment of deep vein thrombosis and several cardiovascular conditions. Some of the mediators are histamine, heparin, leukotrienes, serotonin, chemotactic factors, tryptase, chymase and prostaglandins. Comparison by controlled clinical trial of streptokinase and heparin in treatment of life-threatening pulmonay embolism. Acetylsalicylic acid impairs the platelet release reaction and this platelet function defect combined with the anticoagulant effect of heparin may produce a hemorrhagic tendency. Low-molecular-weight heparin was designed to behave more predictably in the body, thereby making monitoring unnecessary. Misreading of the label has led to dangerous and deadly heparin overdoses. More than a million multiple-dose vials of heparin are sold each month in the United States, and about half of those are manufactured and distributed by Baxter. The left arterial cannula was removed and an intravenous heparin infusion commenced with topical glyceryl trinitrate spray applied over the ischaemic area. A year ago, Baxter International and APP Pharmaceuticals split the domestic market for heparin, an anticlotting drug needed for surgery and dialysis. In clinical studies carried out both on healthy volunteers or in patients, heparin and LMW heparins have repeatedely been repeted to enhance or to unaffect fibrinolysis. Oxygen therapy, iv nitrate and heparin, oral acetylsalicylic acid and proton pomp inhibitor treatments were administered and thrombolytic treatment was not given. Heparin Lock Flush Solution, USP is a sterile, nonpyrogenic, isotonic preparation of heparin sodium injection, USP with sodium chloride in water for injection. She has failed courses of therapy with antimuscarinics, tricyclic antidepressants, pentosan polysulfate, intravesical lidocaine, and heparin therapy. Venous congestion can be treated with elevation, dressing release, external bleeding through nail plate removal, or with the use of leeches or heparin soaked pledgets. Packed with granules of histamine, heparin and other chemical mediators, mast cells degranulate, releasing their contents, in response to the presence of allergens. For unstable angina the treatment is a daily 300 mg dose of aspirin, and injectable anticoagulants such as Heparin are administered in hospital. Heparin is a mucopolysaccharide produced by the body that's responsible for keeping your blood from clotting. Heparin is a glycosaminoglycan polysaccharide with a carbohydrate backbone consisting of alternating uronic acid and hexosamine. Show More Sentences Heparin was discontinued and an emergency order for Hirudin from the regional medical center was placed. Heparin is a polyanion chemical compound that has negative charges. Examples from Classical Literature At the time, we were using reagents from two different manufacturers and PTT reagents with three different degrees of sensitivity to heparin. Whenever possible, administer the heparin as an intravenous infusion and not as a bolus dose. Find more words! 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What is the adjective for heparin? What is the noun for heparin? Use our Sentence Generator Nearby Words HEPA hep heorot Henze hentai Henson heparinized hepatectomy hepatic hepatica hepatitis hepatobiliary 7-letter Words Starting With h he hep hepa hepar hepari