| However, the clinical significance of peripheral erythroblastosis after hematopoietic stem cell transplantation has not been evaluated. |
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| The pharmacist also offered tablets and injectable medicines for the hematic and hematopoietic systems. |
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| At one point, hematopoietic stem cell transplantation was regarded as a draconian measure or last option for patients in these categories. |
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| The progenitors of osteoclasts are from the hematopoietic cell line and the osteoblasts originate from the marrow stroma. |
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| The remainder of the marrow showed a good hematopoietic reserve and slightly increased reticulin. |
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| These influences all contribute to an environment that allows hematopoietic progenitor cells to proliferate and differentiate normally. |
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| Subcutaneous injections of benzol in rabbits produce marked destructive changes in the hematopoietic organs, especially in the myeloid tissue. |
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| Attempts at growing hematopoietic stem cells outside the body for clinical transplantation have not been encouraging. |
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| For example, brain and hematopoietic stem cells give rise only to neural tissue and blood cells, respectively. |
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| There is usually scant osteoblastic or osteoclastic activity, and often there is a marrow component with fat or hematopoietic elements. |
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| In fact, hematopoietic stem cells were discovered in Canada some 25 to 30 years ago. |
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| Expansion of hematopoietic progenitors ex vivo is currently investigated as a means of reducing cytopenia following stem cell transplantation. |
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| This allowed us to quantitate efficiency of recovery of viable hematopoietic progenitor cells from cord blood stored frozen 15 years ago. |
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| Despite this, the use of hematopoietic stem cell transplants is being explored for conditions such as heart disease or autoimmune disorders. |
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| Cross reactivity was absent with WSSV-free or infectious hypodermal and hematopoietic necrosis virus-infected Penaeus vannamei samples. |
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| It is also used for prophylaxis among allogeneic hematopoietic stem cell transplant recipients and selected high-risk cancer patients. |
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| The cord blood will then become available to a candidate for a transplant of hematopoietic stem cells. |
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| In bone marrow, hematopoietic stem cells are anchored to osteoblasts of the trabecular bone and to blood vessels. |
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| The vector was used to transduce ex vivo, hematopoietic stem cells that were then transplanted into previously irradiated knockout mice. |
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| Consistent with our observations, Suratt and colleagues have reported chimerism in lungs using human lung samples after hematopoietic stem cell transplantation. |
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| Dr. Sauvageau's teams has also developed the use of recombinant proteins allowing for the expansion of the hematopoietic stem cells. |
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| The current release contains 11 reference maps from human hematopoietic and lymphoid cell line samples. |
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| The hematopoietic growth factors are potent regulators of blood cell proliferation and development in the bone marrow. |
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| The degree to which transplanted hematopoietic stem cells are able to colonize other tissues is exceedingly small. |
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| Furthermore, the scientists performed secondary bone marrow transplantations to confirm the expression of the therapeutic cassette in primitive hematopoietic stem cells, as well as absence of toxicity due to the treatment. |
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| Disease-like infectious hematopoietic necrosis is clearly a major threat. |
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| Since then, her team has defined the mechanisms by which oncogenes perturb molecular networks in hematopoietic cells, causing cell differentiation arrest and the onset of a preleukemic state. |
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| Chelatable cellular copper modulates differentiation and self-renewal of cord blood-derived hematopoietic progenitor cells. |
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| By extrapolation from laboratory studies, it is very likely that transplanting hematopoietic stem cells collected from the organ donor and developed in the laboratory could avoid rejection of this organ. |
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| In between the trabeculae of cancellous bone resides the hematopoietic bone marrow. |
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| While the bone marrow was initially cleared of all hematopoietic elements, including tumour cells, leukemia eventually recurred in all treated patients. |
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| Homologous use: refers to intended therapeutic use of cells within their native physiological context, for example, the transplantation of hematopoietic stem cells to regenerate the blood. |
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| A method for the ex vivo expansion of multipotential hematopoietic cells, comprising: culturing the cells with a combination of cytokines comprising soluble interleukin-6 receptor, interleukin-6 and stem cell factor. |
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| Our approach is to use transgenic mice, retrovirus-mediated gene transfer, and bone marrow transplantation, to deliver engineered hematopoietic precursors to hemophilic mice. |
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| Our research team studies the mechanisms that determine the generation and diversification of blood cells from a very small number of multipotent hematopoietic stem cells. |
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| These autoantibodies react with the hematopoietic cells, and then the histiocytes phagocytose these cells. |
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| Objectives: To improve the efficacy and safety of gene modification techniques for hematopoietic stem cells for treating rare monogenic diseases, but also to spread the knowledge by facilitating the exchange of experiences. |
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| Until now the field of bone marrow transplantation has been limited to procedures and technologies that expand hematopoietic stem cells only. |
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| Use of human growth hormone for the manufacture of a medicament for stimulating hematopoiesis and immune reconstitution in human patients not to be administered before 30 days post-transplantation of hematopoietic stem cells. |
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| Work with experimental animals has shown that transplants of hematopoietic stem cells can occasionally colonize other tissues, with the transplanted cells becoming neurons, muscle cells, or epithelia. |
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| Outside of the hematopoietic and stratified epithelia systems there is little clinical experience with the toxicities associated with infusion or transplantation of stem cells or their derivatives. |
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| During and following treatment, the patient's hematologic profile should be monitored regularly to determine the degree of hematopoietic suppression. |
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| Within these spaces are bone marrow and hematopoietic stem cells that give rise to platelets, red blood cells and white blood cells. |
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| Progenitor cells such as the hematopoietic stem cell divide in a process called mitosis to produce precursor cells. |
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| Adrenal myelolipoma is a benign tumour-like lesion composed of mature adipose tissue admixed with hematopoietic elements of various proportions. |
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| Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell transplant recipients. |
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| Direct observation of hematopoietic progenitor chimerism in fetal freemartin cattle. |
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| Allogeneic bone marrow transplants are often performed following high-dose chemotherapy, which is used to destroy all the cells in the hematopoietic system in order to ensure that all cancer-causing cells are killed. |
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| Multi-dose Toxicity: Studies in the mouse, rat and dog with valganciclovir demonstrated that the reproductive, hematopoietic, renal and gastrointestinal systems were the main organs for induced toxicity. |
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| Summary: Research suggests that the transmission of the infectious hematopoietic necrosis virus from farmed salmon to wild salmon may have been a factor in the collapse of the Fraser River sockeye population. |
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| If only one of the ten proteins allows hematopoietic stem cells to be multiplied in humans, we will be able to obtain the quantities of cells necessary to perform transplants. |
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| Sucralfate has no effect on the cardiovascular system or central nervous system and on the hematopoietic system including blood coagulation factors. |
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| Frequent evaluation of electrolyte balance, and renal and hematopoietic function is recommended during therapy when high doses of intravenous aqueous penicillin G sodium are used. |
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| Regular assessment of cardiovascular, hepatic, hematopoietic and renal function should be performed in all patients during the dosage stabilization period. |
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| Within the thymus, thymic epithelial cells provide key inductive microenvironments for the development and selection of T cells that arise from hematopoietic progenitors. |
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| The new data show that hESCs can be used to produce hematopoietic cells at efficiencies comparable to human cord blood and mobilized peripheral blood. |
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| Mutations in TET2 are known to lead to aberrant changes in DNA methylation patterns that are strongly associated with leukemic transformation and hematopoietic malignancies. |
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| Leukemias are clonal, neoplastic proliferations of immature cells of the hematopoietic system, which are characterized by aberrant or arrested differentiation. |
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| This protein is a receptor for leptin and is involved in the regulation of fat metabolism and of a novel hematopoietic pathway required for normal lymphopoiesis. |
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| Within the marrow of the bone there are also hematopoietic stem cells. |
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| Critical shortfall in the supply of matched tissue for transplantation creates an urgent need for alternative sources of hematopoietic stem cells. |
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| Hematopoietic stem cells, rich sources found in the umbilical cord and placenta, are precursors of mature blood cells. |
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| Mycoplasmal Infections Prevent Apoptosis and Induce Malignant Transformation of Interleukin-3-Dependent 32D Hematopoietic Cells. |
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