| No interactions based on specific drug-drug interaction studies have been observed with losartan, fibrates, or atorvastatin. |
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| Concomitant Administration with fibrates: The co-administration of ezetimibe with fibrates other than fenofibrate has not been studied. |
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| So it made sense to see if fibrates also helped Type 2 diabetics who were taking statins. |
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| However, the associations of hypertriglyceridaemia and low HDL cholesterol with poor outcomes, together with the limited trial evidence, lead also to strong recommendations over use of fibrates. |
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| Addition of fibrates to simvastatin typically provides little additional reduction in LDL-C, but further reductions of TG and further increases in HDL-C may be obtained. |
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| The combined use of pravastatin and fibrates should generally be avoided. |
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| A handful of reports show that glitazones, fibrates, and biguanides modify the host response to infection and improve survival in experimental influenza, even in the absence of antiviral treatment. |
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| The guidelines also address the issue of management of serum triglyceride and HDL cholesterol levels, and conclude that management with fibrates is indicated if serum triglyceride levels are raised. |
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| The clinical studies have included short and long-term, placebo-controlled and comparative studies versus statins, fibrates, acipimox and probucol. |
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