| Polymerase chain reaction primer pairs were designed for exons 2-12 outside the exonic borders. |
|
| Therefore, this gene is a chimera consisting of the first exon of CG11779 and the second and third exons of Adh. |
|
| TpnI 6a exons, the transcripts of which are mainly expressed in larval hypodermic muscles, may have evolved similarly. |
|
| The structure of the invertase genes are fairly similar, each containing between six and eight exons. |
|
| All of them contained usually short fragments of coding sequences corresponding to exons of single-copy genes. |
|
| As a result, the protein sequences encoded by these exons are nearly identical between the two species. |
|
| He concluded that recombination had separated the genealogical histories of introns and exons within these genes. |
|
| Sequence data for each gene encompassed all coding exons and the intervening introns. |
|
| The exons of the entire or the shortened dystrophin gene can be transferred into muscle cells by viruses, plasmids, or myoblasts. |
|
| In the vWF gene, the B and C domains triplicated and duplicated, respectively, while the MUC6 gene lost several exons coding for the D4, B, and C domains. |
|
| Exon skipping consists in intervening during transcription of the gene into protein to eliminate the exons carrying genetic defects. |
|
| More importantly they succeeded in pinpointing them, often in unexpected places like right at the heart of exons. |
|
| The genes of multicellular organisms consist of active sections, exons, and inactive ones, introns. |
|
| If she is a carrier, the intensity of the bands after electrophoresis are only reduced to half of normal if one or more exons are deleted. |
|
| Moreover, most genes are split up into segments, known as exons, that are separated by long stretches of meaningless drivel. |
|
| The process of removal of the introns and subsequent rejoining of the exons is called RNA splicing. |
|
| The segments of DNA or RNA coding for protein are called exons, and the noncoding regions separating the exons are called introns. |
|
| The intron is twisted into a loop and excised, and the exons are linked together. |
|
| To overcome this problem, we tested an approach which exchanged the last exon or the last exons of the titin messenger. |
|
| If a boy has a deletion in the dystrophin gene, not only are one or more exons missing but also the markers in the introns between them. |
|
|
|
| This can recognise the exons in an open reading-frame, work out the resulting sequence of amino acids and then calculate how the resulting chain should fold up. |
|
| They found that the segments of DNA that coded for proteins, now called exons, were separated by long stretches of DNA, now called introns, that did not contain genetic information. |
|
| The mutations identified by the collaboration are found in the next-to-last and last exons of the gene which result in disruption of the reading frame in the first instance and the appearance of a stop codon in the second. |
|
| Mutations in K-ras gene exons 1 and 2 were initially screened by nonradioactive PCR-SSCP analysis, according to the described method. |
|
| Exons therefore define the structure of the protein built from the gene in question. Genes from eucaryot cells are often made of a sequence of exons separated by introns. |
|
| A gene is made up of introns and exons, with the latter designating the encoding part of the gene, which contains the information necessary for synthesis of the protein. |
|
| These are DNA sequences in the introns between the exons which are almost always differently arranged on an individual chromosome, and they also have different lengths so that the two chromosomes can be distinguished. |
|
| They are separated by specific molecular structures as the exons which enable of doing proteins with information and extremely precise genetic processes organizations, and the introns which would be without action. |
|
| The new tests include comprehensive testing for BRCA1 and BRCA2 encompassing an analysis of all exons and adjacent intronic regions. |
|
| The gene therapy approach based on an exon-skipping strategy acts at the level of splicing of messenger RNAs and aims to restore the missing protein by eliminating the exons which carry the genetic defect. |
|
| However, the amplification of the exons is not easy to control. |
|
| Through the phenomenon of alternative splicing, by which a variety of mRNAs can be generated by multiplying combinations of exons, a single gene can code for several proteins. |
|
| The opsin sequences have 364 amino acids divided into six exons separated by five 'neutral' segments or introns. |
|
| Interleukin-10 is a potent pleiotropic cytokine, located on chromosome 1q31-32, consisting of five exons and four introns. |
|
| Before these genes form any protein, cells cut out all the introns and splice together the remaining exons. |
|
| Once the introns are removed, the spliceosome can stitch together exons in various combinations. |
|
| For the analysis of the COL4A4 gene, all the exons including splicing sites were amplified by PCR and screened by direct sequencing analysis. |
|
| This revealed MOG specific variants that encoded different exons. |
|
| Luckily, the boundaries between introns and exons are marked. |
|
| Exons were assigned by comparison of messenger RNA and genomic sequences. |
|
