| Witte et al. determined that subtoxic concentrations of membrane-damaging compounds enhanced the cytotoxicity of hydrophilic xenobiotics. |
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| In vitro, these peptides inhibited cytotoxicity and differentiation of cytotoxic T cells. |
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| Thus it appears that PHP-mediated cytotoxicity proceeds through both membrane and mitochondrial photosensitization. |
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| The initial photooxidative injury triggers a number of responses, including direct cytotoxicity within the tumor microenvironment. |
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| We attributed the reduced cytotoxicity at higher repetition rates to the contribution of the oxygen-independent mechanism. |
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| Qualitatively, no difference was observed in the cytotoxicity of unheated, heated and ultra filtered culture supernatants of isolates. |
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| None of the sterols tested at this level induced cytotoxicity as measured by lactic dehydrogenase release. |
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| All the three proteoglycans stimulated mice thymocyte and splenocyte proliferation and elevated cell cytotoxicity. |
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| It has been suggested that sequestration of bile acids by intracellular bile acid binding proteins may also protect cells from bile acid cytotoxicity. |
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| Hence, in a certain degree, compound 8a might have cytotoxicity selectively towards Hela. |
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| Data should include cytotoxicity and viability determination, colony counts and mutant frequencies for the treated and control cultures. |
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| It may be useful to determine cytotoxicity and solubility in a preliminary experiment. |
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| As for safety, most drugs caused the usual signs of cytotoxicity, including neutropenia, thrombocytopenia, fever, infections, and gastrointestinal toxicity. |
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| None of the two compounds did show any cytotoxicity effect on human THP-1 cells. |
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| We evaluate the cytotoxicity in vitro of 34 pharmaceuticals from different classes and modes of action. |
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| It seems not to be particle type specific and can occur with any poorly soluble particle with low cytotoxicity. |
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| Retained cytotoxicity in vitro in the presence of efflux pumps that confer drug resistance to other chemotherapeutic agents. |
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| The concept of lung overload applies specifically to poorly soluble particles with low cytotoxicity. |
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| Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. |
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| Macrophage cytotoxicity against schistosomula of schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. |
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| Biological screening of cyanobacteria for antimicrobial and molluscicidal activity, brine shrimp lethality and cytotoxicity. |
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| The cytotoxicity assay measures the production of Toxin B and the cytopathologic effect of a stool-sample preparation on cultured cells. |
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| Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity. |
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| Among the criteria to be considered when determining the highest concentration are cytotoxicity, solubility in the test system and changes in pH or osmolality. |
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| The ability to generate phosgene and phosgene hydrolysis products determines which tissue regions in the liver and kidney are sensitive to the cytotoxicity of chloroform. |
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| No cytotoxicity was observed for fullerenes. |
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| IgG or IgM binds to the new antigen on the blood cells, lysing blood cells via either complement fixation or antibody-dependent cell cytotoxicity. |
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| The biological relevance of data should be considered: i.e. parameters such as inter-animal variation, dose response relationship and cytotoxicity should be taken into account. |
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| If cytotoxicity is found, both the concentration range and the intercept of individual concentrations should be set in such a way as to allow the fit of a curve to experimental data. |
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| If cytotoxicity occurs after seven days, subcultivation shall be performed once and the cells shall be incubated to achieve the total of 28 to 36 days incubation from the primary inoculation. |
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| In carcasses from wild boar it might be the method of choice, if the material is autolysed and virus isolation is not possible any more due to cytotoxicity. |
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| No indication of cytotoxicity was recorded in this test. |
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| Amongst the criteria to be taken into consideration when determining the highest amount of the test substance to be used are the cytotoxicity and the solubility in the final treatment mixture. |
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| Numerous subchronic or chronic experimental inhalation studies have been conducted with poorly soluble particles such as titanium dioxide, coal dust, carbon black and talc that are considered of low cytotoxicity. |
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| The cytotoxicity of 22 sesquiterpenoid unsaturated dialdehydes, as determined by the neutral red absorption assay and by protein determination. |
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| These factors, coupled with the cytotoxicity of previous synthetics, were part of the impetus for developing the fibrinogen adhesive, he says. |
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| They measured and compared the cytotoxicity induced by arsenicals and their metabolic profiles in vitro. |
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| The production of cytotoxin by culture isolates with characteristic morphology was determined with the cytotoxicity assay. |
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| Versalloy HC helps us meet today s most stringent cytotoxicity and extractability requirements for critical pharmaceutical process applications. |
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| Treatment induced cytotoxicity in the cells was determined using the ATP assay. |
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| By facilitating efflux of drugs from the intracellular domain, these proteins reduce cytotoxicity and thus confer drug resistance. |
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| Measurements of tumoroid size and numbers revealed a dose-dependent cytotoxicity in treated tumoroids when compared to untreated controls. |
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| Inhibition of steroid sulphatase by estrone-3-O-sulphamate led to a shift of the minimum effective concentration of PS against AMPA cytotoxicity from 30 to 10 microm. |
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| Exposure of these two malignant cell lines to RF alone also produced some cytoxicity, although significantly less cytotoxicity than the GNP RF combination. |
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| Gentian violet was used as positive control in the cytotoxicity assays. |
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| Relationship of cytochrome P450 activity to Clara cell cytotoxicity. |
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| In addition, in this survey, the inhibition of infection in macrophages and cytotoxicity effects of both the extracts on murine macrophage cells were investigated. |
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| Synthesis and cancer cell cytotoxicity of substituted xanthenes. |
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