How to use bone marrow in a sentence

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Sentence Examples Common sites of metastases include liver, bone, bone marrow, extradural space, orbits and skin. Bearded vultures are the only living birds known to access bone marrow, which they do by dashing bones onto rocks from great heights. Chemotherapy and total-body radiation therapy given as part of a bone marrow transplant can cause diarrhea. One, a 20 year old female, had deposits in the brain, liver, lung, bone marrow, adrenal glands, and ovaries. The bone marrow is responsible for formation of blood components such as the white blood cells and platelets. A widower, whose wife died from leukaemia last year, is appealing to people to join the bone marrow register on her birthday. You can donate blood, bone marrow, even kidneys and even part of your liver as a living donor. The bone marrow is also able to make other types of blood cells, such as red blood cells and platelets. As the new bone marrow also produces red cells and platelets, you are also at risk from anaemia and bleeding. Scientists have long known that bone marrow stem cells regenerate blood cells. The BBMR is a division of the National Blood Service, which works in co-operation with the other UK bone marrow donor registries. The discovery suggests that many other fossil bones may contain well-preserved remnants of bone marrow, the scientists say. A year ago today, she was undergoing a transatlantic bone marrow transplant in a last-ditch attempt to beat leukaemia. An equivalent number of reticulocytes are released daily from the bone marrow. The bone marrow helps regulate the number of white blood cells in the body. The myeloid lineage gives rise to the rest of the white blood cells or leukocytes, which all derive from the bone marrow in adults. In people with leukemia, the bone marrow produces a large number of abnormal white blood cells. Benzene is especially noxious, with the ability to cause bone marrow cancer and leukemia. There are two basic reasons for carrying out bone marrow transplantation for leukaemia and lymphoma. When a child has leukemia, large numbers of abnormal white blood cells are produced in the bone marrow. Show More Sentences Today, she is desperately fighting for her life in hospital and a bone marrow transplant is the only thing that could cure her. Because this disease is virtually always fatal due to the profound bone marrow aplasia, management is not well defined and is rarely successful. Patients undergoing such treatment are at high risk for bone marrow aplasia. We are appealing for healthy people to volunteer to undergo a blood test to see if their bone marrow would be suitable. Any tissue can be biopsied, including the liver, lung, brain and bone marrow. To confirm a suspected second relapse, a bone marrow aspirate and core biopsy were performed. After synthesis in the bone marrow, they migrate to the systemic circulation and on to the lung. For example, leukemia is a cancer that involves blood, bone marrow, the lymphatic system and the spleen but doesn't form a single mass or tumor. There is a generalized infection with involvement of the liver, spleen, bone marrow, and lymph glands. The lymph node and bone marrow biopsy specimens were tested by paraffin section immunohistochemistry. He was rushed to Balboa, where doctors began extensive tests, including a lymph node and bone marrow biopsy. If you are not able to have an autologous transplant, the doctors will try to find a bone marrow donor for an allogenic transplant. What's much safer is an autologous transplant where a person's own stem cells are harvested either from their blood or bone marrow. If you have had an autologous transplant, your body will not reject the bone marrow. White blood cells are produced by the bone marrow, the soft spongy centre of bones. In the EU, approximately 13,000 cancer patients undergo autologous bone marrow transplant each year. The concept that autologous bone marrow stem cells target a specific organ and replace diseased cells is particularly attractive. Similarly, workup of the bone marrow for lymphoma and plasma cell malignancies is aided by immunophenotyping. The term refers to any of a group of malignant diseases of the bone marrow and other bone forming organs. Divide veal, scallions, Brussels sprouts, sake, bone marrow and bouillon into four bowls. Show More Sentences In some cases you may be able to exchange cards or letters with the person who received your donated bone marrow. Autologous bone marrow transplantation was being viewed in a different light. Overall it is very well tolerated, with a low incidence of bone marrow suppression. Stem cells are cells taken from bone marrow which have the ability to grow into several different types of tissue. Definitive treatment of the disorder relies on reconstituting the patient's bone marrow. For this reason, close relatives are often the donors of choice in bone marrow transplantation. In other areas, such as blood and bone marrow donation, living donors are the norm. His sister was found to be the one-in-a-million bone marrow match he needed. In general, magnetic resonance is excellent for imaging soft tissue and bone marrow. His topic was the regeneration of damaged heart muscle, by use of bone marrow stem cells. It is usually found in the lymph nodes but can also spread to involve other organs such as the spleen and bone marrow. If you require a bone marrow transplant a compatible donor will need to be found. He donated bone marrow at a hospital in London before it was transported to America. During a transplant, healthy bone marrow will be fed into your blood stream. Autologous transplants are stem cells from the patient's own bone marrow or peripheral blood. The bone marrow cells will be collected using a needle and syringe, with no cutting or stitching involved. Stem cells have been isolated from the central nervous system, bone marrow, and blood of adults. Medical opinion holds that if the patient's body doesn't reject the bone marrow within five years, it is a perfect match. Chronic inhalation abuse may also cause bone marrow depression resulting in leukopenia, anemia, thrombocytopenia, leukemia, and hemolysis. It sparked a massive media appeal to find bone marrow donors for the four youngsters. Show More Sentences Primary lymphoid organs in the thymus and bone marrow constitute the major site of lymphocyte development. The lymphatic system consists of lymph nodes and vessels, the thymus, spleen and bone marrow. Leukocytes are produced or stored in many locations throughout the body, including the thymus, spleen, and bone marrow. Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow. She had megaloblastic changes in the bone marrow and chronic severe liver disease. Three of these children revealed megaloblastic changes in bone marrow aspiration though their serum vitamin B12 and folate levels were normal. But now his best chance of beating the disease is if a matching bone marrow donor can be found. Metastatic foci were also seen in the mesenteric lymph nodes, pancreas, stomach, visceral pleura, and bone marrow. This does not affect the egression of cells from the bone marrow into the blood. Case 2 involved a 3-year-old boy who received a mismatched unrelated bone marrow transplant for metachromatic leukodystrophy. The major parts of the system are the bone marrow, spleen, thymus gland, lymph nodes, and the tonsils. Other parts of the lymphatic system are the spleen, thymus, bone marrow and tonsils. Many different tissues can be transplanted such as whole organs like the heart, or cells as in bone marrow transplantation. We report the case of a woman who had undergone a successful allogeneic bone marrow transplant for acute myeloid leukemia. In 2 cases, a bone marrow trephine biopsy was also available for examination. By implanting the bone marrow mononuclear cells, we deliver endothelial progenitor cells and vascular growth factors at the same time. If you would like to register as a potential bone marrow donor on the British Bone Marrow Registry, you must also be a regular blood donor. Red blood cells are produced in the bone marrow and circulate in the bloodstream before they are broken down in the spleen. Cord blood, from the umbilical cord and placenta, contains cells which can provide an alternative to bone marrow transplants. Stem cells are harvested from bone marrow, umbilical cords, the brain and spinal cord and other tissues. Show More Sentences Beth underwent a life saving bone marrow transplant when she was five after a mystery donor was found in Germany. Currently people from these communities are under-represented on the blood and bone marrow donor registers. They tried to give her a bone marrow transplant but her bones rejected every bone tissue that was given to her. As in our case, the severity of peripheral neutropenia did not correlate with the cellularity of the bone marrow myeloid compartment. The bone marrow was markedly hypocellular with leftshifted myeloid maturation. Some evidence indicates that in chronic myeloid leukaemia, bone marrow transplantation can prolong life if performed during its chronic phase. The journey from the bone marrow to vascular endothelium or myocardium is divided into stages. Bilateral bone marrow biopsies and a unilateral bone marrow aspiration were performed. Then a hollow needle is inserted into the bone, and a syringe is used to draw out the liquid-like bone marrow. Also during this time, the bone marrow suppressive effect of nitrogen mustard was discovered. Mum Allison is hoping to hear news today on whether or not she can donate bone marrow to Joshua. A side effect of such therapy is bone marrow suppression that adversely affects the patient's ability to generate hematopoiesis. It is in a critical stage and the only way to save her is through a relatively harmless bone marrow transplant. Her battle with the disease included surviving two harrowing bone marrow transplants. The stem cells were harvested from the patient's own bone marrow and injected into the ventricle. A similar situation has been noted in paediatric oncology, with a lower than expected number of referrals for bone marrow transplant. She carried a heavy workload, much involved in paediatric oncology and the early days of bone marrow transplantation. Cells are aspirated from the bone marrow of the crest of the hip bone using a needle and syringe with local anesthesia. This requires a bone marrow examination from the crest of the hip bone using local anesthesia. Some bones also bear evidence that hominins used fist-sized stones to break them open to acquire bone marrow. Show More Sentences Peripheral blood stem cell or bone marrow transplantation often leads to chimerism, wherein the patient possesses a mixed cell population. Short-term effects of IV-CPA pulses include bone marrow suppression and significant hyperemesis. A gram-positive coccus was isolated from the bone marrow of a 5-year-old patient with leukemia. However if the cord blood transplant had not been successful, they had a perfectly matched bone marrow donor in the person of Adam, the infant. Two laboratories collaborated in this project, one analysing bone marrow cells and the other analysing gut cells from the same animals. The corrected reticulocyte index should be elevated in patients with an acute anemia but a competent bone marrow. The bone marrow was replaced by an infiltrate of blast cells with medium-sized nuclei, multiple nucleoli, and moderate amounts of cytoplasm. In a successful transplant the new bone marrow migrates to the cavities of the large bones, engrafts and begins producing normal blood cells. They inject me with the new bone marrow and hopefully it will engraft and start to make new, healthy cells instead of cancerous ones. After a second infusion, a few weeks later, all of the patients showed engraftment in one or more sites, including bone, skin and bone marrow. A team of intrepid roller skaters aim to cover 1,500 miles across Europe in aid of a bone marrow charity. Patients receiving total body irradiation for bone marrow transplant conditioning must also be considered at risk. Tissues such as corneas, skin, bone, bone marrow, cartilage, tendons, veins, and fascia also can be transplanted successfully. The iliac crest bone marrow biopsy is the gold standard for detecting of bone marrow metastases in small cell lung cancer. Just weeks before competition, she donated bone marrow to her critically ill brother. In vivo cytogenetic studies suggested the induction of chromosome damage in Chinese hamster bone marrow cells. The bone marrow was re-evaluated at the second relapse by morphology, morphometry, DNA ploidy, flow cytometry, and cytogenetics. It uses genetic fingerprinting to identify tiny leukaemia cells from a sample of bone marrow. We do not know whether the tumor in the bone marrow represents a primary or metastatic process. Like him, Alice is very brave and deserves a chance for a bone marrow transplant. Show More Sentences The bone marrow is also hypercellular with varying amounts of granulocytic and erythroid hyperplasia. In emaciated animals, serous atrophy occurs at these depot sites and in the bone marrow cavity. The tumor disseminated early to the lungs, lymph nodes, bone marrow, and spleen and ran a fulminant course. These small, enucleate cells are produced from large parent cells, the megakaryocytes, in the bone marrow. The bone marrow was hypercellular with mildly increased eosinophils and plasma cells. As the immature cells accumulate in the bone marrow, they replace the normal myelocytic cells, megakaryocytes, and erythrocytic cells. Severe anemia due to bone marrow aplasia is often a major complication as a result of viral replication in erythroid precursors. No membrane expression of E-cadherin was present in any of the 14 bone marrow biopsy specimens from patients with erythroleukemia. If you haven't been tested for bone marrow donation, consider getting tested. The decalcification process did not affect the immunodetection with CD10 since positive reactivity was noted in decalcified bone marrow core biopsies. Although the extension of infection appeared to be primarily direct, lesions suggesting hematogenous dissemination were occasionally noted in bone marrow and skin. If the results are abnormal, you may be referred to a hematologist, a doctor who specializes in diagnosing and treating bone marrow and blood disorders. Increasingly senior educational roles were capped by 18 years as staff development instructor in oncology, haematology and bone marrow transplant. The histologic, cytochemical, and immunohistochemical features resembled a carcinoid tumor, and metastasis to the bone marrow was considered initially. Under normal conditions of hemopoiesis, the bone marrow acts as a site for the turnover and traffic of mature leukocytes to the peripheral circulation. In lieu of bone marrow transplants, scientists hope to use stem cells to serve as the future vectors of mutant CCR5 proteins. In August 2012, anchor Robin Roberts took a leave of absence for a bone marrow transplant. The bone marrow of the dead soldiers was depleted dramatically, and their lymph nodes had shriveled away. The stem cells came from Hannah's bone marrow, extracted with a special needle inserted into her hip bone. By Election Day, I had been through a bone marrow transplant and was on the mend. Show More Sentences At that time, she faced a race against time to find a bone marrow donor who matched her rare blood type, after being diagnosed with chronic myeloid leukaemia. The bone marrow, which is in the cavity present in the center of bones, is the organ responsible for the production of red blood cells, white cells and platelets. The patient underwent a staging workup that included computed tomography scans of the chest and abdomen and bilateral bone marrow biopsies and aspirates. In addition, many patients are waiting for blood or bone marrow donations. You explained that Alice has a very rare tissue type and that, although efforts continue, searches of the bone marrow registries worldwide have not so far found a good match. The percentages of aneuploid bone marrow leukocytes were higher than those of aneuploid sperm for the two upper THH dose groups and for the positive control group. Then normal bone marrow cells, donated from a close relative or carefully removed from the person's own bone marrow, are infused into the bloodstream with a drip. Lethally irradiated mice were grafted with the bone marrow cells. He died after a second bone marrow transplant could not cure the disease. Herein, we report a case of monoclonal B-cell proliferation involving lymph nodes, bone marrow, and peripheral blood in a patient with Whipple disease. Evaluation of the bone marrow revealed a small monoclonal population of cytoplasmic kappa light chain-restricted plasma cells in an otherwise normocellular marrow. The meeting followed years of campaigning by the parents after their daughters were diagnosed with severe blood disorders that required bone marrow transplants. When performing microarrays to evaluate leukemias, normal and leukemic cells found in blood or bone marrow are first separated by density gradient centrifugation. At the end of the antimonial therapy, the bone marrow aspirate did not show any L-D bodies or malarial parasites, and there was no residual lymphadenopathy. Many patients with leukemia only have blast cells in their bone marrow. For bone marrow transplantation, to get a stem cell transplant to work, you need to treat the host with lethal doses of preparative irradiation, which has severe side effects. Further tests, including a bone marrow sample for leukaemia, failed to confirm a diagnosis but the illness was linked to a rare from of pure red blood cell aplasia. I mean, bone marrow transplants and heart transplants and neonatal ICUs are kind of a big deal, no? Even mammals have nucleated red blood cells in their bone marrow. In a recent study in Nature Medicine, normal bone marrow derived cells that were infused into patients suffering from osteogenesis imperfecta, a genetic disease. Show More Sentences Iron staining of the bone marrow aspirate revealed increased storage iron. The safety profile of the formulation is generally favorable, with no demonstrable ototoxicity, nephrotoxicity, bone marrow suppression, or cardiovascular adverse effects. The study also represents the first successful animal model for studying how stem cells from human bone marrow and umbilical cord blood might be used to treat liver disease. After five or six days in hospital Kim was diagnosed with severe aplastic anaemia which is a failure of the bone marrow to produce blood cells and platelets. Expression of a germ cell marker in bone marrow fluctuated regularly with the female mouse's estrous cycle, much like the cyclical rise and fall of certain hormones. As well as the polymorphs and macrophages, there are cells that do not originate in the bone marrow, nor travel in the bloodstream, which can also act as phagocytes. He needs more chemo, plus radiation, and a bone marrow transplant. A bone marrow biopsy can rule out other chronic myeloid disorders. In contrast, autologous transplants usually result in relapse within one year, due to residual disease in the patient, or in the bone marrow preparation. Another important renal response to ischemia is the release of erythropoietin, which stimulates the bone marrow to increase production of red blood cells. To our knowledge, this is the first reported case in which florid parvovirus infection and subsequent recovery was documented by sequential bone marrow examination. Multiple myeloma is a hematological malignant neoplasm of the bone marrow. The results of a computed tomography of the chest, abdomen, and pelvis performed after surgery as well as the results of a bone marrow biopsy were negative. As stated, a bone marrow biopsy was negative for plasma cell dyscrasia in our case, which further supports the diagnosis of a localized plasmacytoma. Human bone marrow is a tissue of complex architectural organization, which includes granulopoietic loci, erythroblastic islets, and lymphocytic nodules. In the process she has faced round after round of blood transfusions and radical hospital treatment to negate the effects of the illness that is destroying her bone marrow. In this disease, which occurs when a child inherits from both parents a particular mutation in a single gene, bone marrow fails to produce enough blood components. A bag containing the retrovirus was connected to a bag of his bone marrow. Before a transplant takes place, the patient's abnormal bone marrow is destroyed through total body radiation, in combination with the drug cyclophosphamide. In adults, red marrow is mostly found in the bone marrow of the femur, the ribs, the vertebrae and pelvic bones. Show More Sentences A 14-16 G bone marrow aspiration needle with an interlocking stylet was used for collection. Autologous bone marrow transplanation for extramedullary plasmacytoma presenting as adrenal incidentaloma. In between the trabeculae of cancellous bone resides the hematopoietic bone marrow. Effects on bone marrow cells of oral treatment with podophyllotoxin derivatives in rheumatoid arthritis. The doctors took bone marrow from his own blood, grew the cells and he became his own transplantee. Until now the field of bone marrow transplantation has been limited to procedures and technologies that expand hematopoietic stem cells only. Moreover, the serum parathormone and vitamin D levels were also normal, and bone marrow aspiration and a biopsy yielded nothing abnormal. No other important findings were noted, except for an evident increase in myeloid series and megakaryocytes on bone marrow aspiration and biopsy. Other mycotoxins include trichothecenes and zearalenone, compounds known to injure the intestines, bone marrow, lymph nodes, spleen, and thymus. Lymphadenoid tissue includes the lymph glands, spleen, bone marrow, and tonsils, and the lymphatic tissue of the organs and mucous membranes. He returned to London, where he was diagnosed with an inoperable prostate cancer, which had spread to his bone marrow. Isotopes and compounds of plutonium are radioactive and accumulate in bone marrow. Other types of tissue found in bones include bone marrow, endosteum, periosteum, nerves, blood vessels and cartilage. Within these spaces are bone marrow and hematopoietic stem cells that give rise to platelets, red blood cells and white blood cells. Bone marrow, also known as myeloid tissue in red bone marrow, can be found in almost any bone that holds cancellous tissue. Two patients treated with both of these therapeutic modalities showed transient bone marrow hypocellularity. Blood cells that are created in bone marrow include red blood cells, platelets and white blood cells. As well as creating cells, bone marrow is also one of the major sites where defective or aged red blood cells are destroyed. Cancers of the bone marrow inside the bone can also affect bone tissue, examples including leukemia and multiple myeloma. Cancers of bone marrow may be treated with chemotherapy, and other forms of targeted therapy such as immunotherapy may be used. Show More Sentences Current therapy includes ATRA, either alone or in combination with chemotherapy, arsenic or bone marrow transplantation. Ryan has acute lymphoblastic leukemia, a malignant cancer that originates in cells in bone marrow. People who are sensitive to chloramphenicol can develop a type of bone marrow depression called aplastic anemia, which can be fatal. Hunting for micrometastases in either sentinel lymph nodes or bone marrow isn't justified for these women, say the researchers. The majority of all the cell type involved in the immune system is produced from common hemopoietic stem cells of bone marrow. Structure Haemoglobin is a large molecule made in the bone marrow from two components, haem and globin. Regular monitoring is required for both treatments, particularly methotrexate to prevent significant bone marrow suppression and hepatotoxicity. Frequent findings included bone marrow hypocellularity, reticulin fibrosis, necrosis, and plasmacytosis. The bone marrow aspiration showed hypocellularity and significantly increased eosinophilicprecursors. Low IPSS score and bone marrow hypocellularity in MDS patients predict hematological responses to antithymocyte globulin. Polycythemia vera is a blood disorder in which the patient's bone marrow makes an excess of red blood cells. Several human studies have been done using bone marrow and fat stem cells for articular cartilage lesions. A drug best known for kick-starting bone marrow to make red blood cells has reversed brain damage due to strokes in test mice. These represent the average size and haemoglobin content of red cells produced in the bone marrow over the last 120 days. Specifically, peripheral blood during preleukemia phase, bone marrow aspiration and biopsy may not be sufficient for diagnosis. This was accompanied by hyperplasia of the normal T lymphocyte population in his bone marrow. Fanconi anemia is a condition of congenital malformation and bone marrow failure predisposing individuals to developing leukemia. Cammie Forbes, 17, who was first diagnosed with leukaemia 10 years ago, was given a life-saving bone marrow transplant by Alistair, eight. Metastases were present in the liver, bone marrow, adrenal glands, thyroid gland, sphenoid sinus, brain, dura, and lungs. Scientists knew where to search, but trying to find stem cells in the bone marrow was like looking for a toothpick in a lumberyard. Show More Sentences Multiple myeloma is a form of blood cancer that arises from plasma cells, a type of white blood cell, found in bone marrow. The doll is held during difficult procedures such as spinal taps or bone marrow aspirations that require the patient to be motionless. Detection of minimal residual disease by immunostaining of bone marrow biopsics after 2-chlorodeoxyadenosine for hairy cell leukemia. In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bonelike tissues. Cytomorphologic examination of the bone marrow slides separately by 2 morphologists into healthy and pathological samples. Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation. At this point of time, bone marrow examination showed no evidence of lymphomatous infiltration. The hallmark of folate deficiency is macrocytic anaemia with megaloblastic change in the bone marrow. A bone marrow aspirate was almost entirely plasmacytoid lymphocytes consistent with Waldenstrom macroglobulinemia. Both studies focused on the effects of a bone marrow growth factor administered to people with small-cell lung cancer. With ALL, the bone marrow releases large numbers of immature white blood cells, or blast cells. Researchers in Sweden, China, and the UK have discovered how a tumor affects a patient's blood count and bone marrow characteristics. These genetically labelled bone marrow cells remylinated a peripheral pattern of mylination reminiscent of schwann cell myelination. The Philadelphia chromosome is an abnormality that sometimes occurs in the bone marrow cells of leukemia patients. Additionally, researchers assessed patients' bone marrow myeloblast counts. The researchers now report that 52 people who had severe GVHD after a previous bone marrow transplant have undergone the novel procedure. In a murine model of allogeneic bone marrow transplantation the drug was shown to improve survival outcomes in mice. Acute haemolysis and impaired bone marrow response are important in this setting. Immediate and delayed neurotoxicity after mechlorethamine preparation for bone marrow transplantation. The bone marrow showed increased megakaryocytes with dysplasia and granulocytes with dysplastic changes and an increased number of blasts. Show More Sentences A bone marrow showed a hypercellular smear with plasmacytosis and increased erythropoiesis with severe megaloblastic features. Knight was diagnosed April 7 with acute myelogenous leukemia, which develops when there is a defect in bone marrow. Comparison of chondrogenic potential in equine mesenchymal stromal cells derived from adipose tissue and bone marrow. There was little bone marrow toxicity and no hemorrhagic cystitis or CNS toxicity. Myelodysplastic syndrome associated with bone marrow fibrosis. Reticulocytes are the youngest erythrocytes released from the bone marrow into the blood and they circulate for 1-2 clays before becoming mature erythrocytes. This iron is distributed throughout the body in hemoglobin, tissues, muscles, bone marrow, blood proteins, enzymes, ferritin, hemosiderin, and transport in plasma. Platelets are small nonnucleated blood cells that have a vital role in hemostasis and thrombosis and are produced in the bone marrow from megakaryocytes. Patients with mutations in the SF3B1 gene frequently had a specific abnormality of red blood cells in their bone marrow, called ring sideroblasts, researchers said. Mesenchymal stem cells are progenitor cells which can differentiate into multiple connective tissues including bone, cartilage, muscle, tendon, bone marrow stroma and fat. Natural killer cells originate in the bone marrow and go through a maturation process that enables them to participate in early control of microbial infections and cancers. As storage cells were observed in the bone marrow aspiration specimen and lysosomal sphingomyelinase activity was low, the patient was diagnosed with Niemann-Pick disease. Long bones, which are found in the limb of tetrapods, are not only important for locomotion and supporting the weight of the body, but also host the bone marrow. In 1996, a 39-year-old French woman was hospitalized in Marseille for chronic myelogenous leukemia, pancytopenia, and allogeneic bone marrow transplantation. Syngeneic bone marrow transplantation is rare in patients with severe aplastic anemia and usually requires pre-transplant conditioning to provide engraftment. But it's for a terrific cause, as the Anthony Nolan is setting up simple new saliva tests to get people to join its bone marrow register and save lives. This process of progressive differentiation occurs within the bone marrow. About Mastocytosis Mastocytosis is a rare disease in which immune cells known as mast cells abnormally build up in the skin, bone marrow and other parts of the body. The disease is classified into cutaneous mastocytosis where the infiltrates are within the skin, and systemic mastocytosis involving extracutaneous organs and bone marrow. Three of these patients had bone marrow edema at the acetabulum, and the other three at the lateral aspects of the femoral heads and the tuberculum majus. Show More Sentences John became the donee of the bone marrow donated by his brother. Acute renal failure due to adenovirus-associated obstructive uropathy and necrotizing tubulointerstitial nephritis in a bone marrow transplant recipient. The pair were diagnosed with a rare medical condition called Familial Monosomy 7 Syndrome in 2013 and both needed bone marrow transplants to save their lives. Previous studies, all done in the laboratory, had suggested that macrophages in the bone marrow act as nurse cells for erythroblasts, which are RBC precursors. In addition, bone marrow biopsies as early as 15 days after transplant show normal cellularity and engraftment of all three major blood cell lineages. Aspirate contained MSCs from bone marrow was placed in heparinized tubes. George oysters with beer granita, foie gras torchons, sweetbreads with emulsified brown butter caper vinaigrette, squab a l'orange and steak with a bone marrow beignet. He was diagnosed with reticular dysgenesis, which is a rare genetic disorder of the bone marrow and the most severe form of severe combined immunodeficiency. The cancer may start from the bone marrow, lymph nodes, spleen, tonsils, thymus or other lymphatic tissues as well as the lymph vessels that connect them. Examination of the biopsy specimens showed that the bone marrow was normocellular and contained macrophages that phagocytized the lymphoid and erythroid elements. Erythropoietin is a complex molecule, first isolated in 1977 and now well-known for its physiological role in the regulation of red blood cell production in the bone marrow. Treatment modalities vary from curettage and bone grafting to trephination with injection of allogeneic demineralized bone matrix and autogenous bone marrow. According to researchers these immune cells are called macrophages whether they reside in the heart or arrive from the bone marrow, Health news reported. Minnetonka, MN, worldwide rights to Busulfex Injection, an intravenous formulation of the alkylating agent busulfan, a drug often used in bone marrow transplantation. A study was designed to evaluate the toxicogenic versus protective effect of cooked and dehydrated black beans on bone marrow and peripheral blood cells of mice. Fatal toxic bone marrow failure associated with clopidogrel. Examples from Classical Literature Pappenheimer brought about similar lesions in rats by the injection of a suspension of bone marrow from a rhachitic animal. Some of these organisms may settle by preference in the bone marrow, others beneath the periosteum, or in the joint. The centres of these tubercules become caseous, and, by fusion of adjacent caseous areas, also cause softening in the bone marrow. Film preparations of bone marrow are best made by the Price-Jones method. When the nurse began transfusing the bone marrow through the IV line, everything became calm. But, at only 40 years old, both Joseph and Myrna have survived cancer and bone marrow transplants. Find more words! 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Translations for bone marrow Use our Sentence Generator Nearby Words bonelike boneless bone-idle boneheads boneheaded bonehead bone-marrow bonemeal bone of contention boner boners bones