A single blastomere is removed from each 8-cell human embryo for the purposes of preimplantation genetic diagnosis. |
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No one has yet converted a single blastomere from an eight-cell embryo into a stem cell line. |
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Another issue raised is that the blastomere and resulting stem cells would not genetically match the patient receiving the cell transplant. |
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Dr. Lanza found that one such cell, or blastomere, could generate embryonic stem cells. |
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Animals have been cloned by three processes: embryo splitting, blastomere dispersal, and nuclear transfer. |
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Although he used discarded human embryos, he said that anyone who wished to derive human embryonic stem cells without destroying an embryo could use a blastomere removed for the test, called preimplantation genetic diagnosis. |
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The technique involves removal of a single cell from an early, eight-cell embryo called a blastomere. |
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For instance, in domestic animals similar experiments were a success as early as 1986, when Willadsen produced the first mammal, a lamb from an oocyte which had received the d iploid nucleus of a blastomere. |
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Generally, a small hole is made in the zona pellucida of an in vitro embryo and the blastomere can be displaced either by liquid or by exerting pressure using a micropipette or by suction. |
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The blastomere theory proposes that they arise from residual pluripotent embryonic cells left behind following a missed abortion or undelivered papyraceous twin. |
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Each blastomere inherits a certain region of the original egg cytoplasm, which may contain one or more regulatory substances called cytoplasmic determinants. |
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We would certainly hope that our patented, proprietary 'embryo-safe' single-cell blastomere technique would be a part of any such conversation. |
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Advanced Cell said it was awarded grants for its blastomere, myoblast, induced pluripotent stem cell and retinal pigment epithelial cell programs. |
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