| In this article, we explore the ability of CARS microscopy to probe axonal myelin in live spinal cord white matter isolated from guinea pigs. |
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| At necropsy these infants have severe brain swelling and hypoxic injury but little axonal shearing and only a thin subdural haemorrhage. |
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| The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems. |
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| Major findings include subdural and subarachnoid hemorrhages and diffuse axonal injury in the brain and retinal hemorrhages in the eyes. |
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| The viral capsid is transported to the dorsal root ganglion in neurons via retrograde axonal flow. |
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| It is also possible, however, that direct compression of axons may induce axonal damage independent of Schwann cell dysfunction. |
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| None of the cases had strongly beta-APP-immunoreactive beaded or swollen axonal segments indicative of axonal damage. |
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| Some cases are due to acute axonal neuropathy, in which glycolipid in the axolemma is targeted. |
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| By incorporating specific peptide motifs into these hydrogels it is possible to create optimal chemical environments for axonal regeneration. |
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| Dr. Yong continues to explore the role of metalloproteinases in regulating myelin formation and axonal growth. |
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| As this nerve damage accumulates, the brain tries to compensate for axonal loss and you may not notice any impairment. |
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| Approximately 75 percent of brain volume is attained after birth, due mainly to extensive axonal myelinisation by glial cells. |
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| After this reattachment, the muscle fibres are able to work again, but these extra axonal sprouts probably cannot sustain forever. |
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| An observation technique dependent on retrograde axonal flow has been used extensively to demonstrate the origin of fibre tracts. |
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| This phenomenon could also be secondary to migration of nanoparticles along the axonal routes, from the olfactory bulbs. |
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| Much of what we know about the mechanisms of myelin and axonal damage in MS is based on examination of the brain and spinal cord after death. |
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| Several molecules and their receptors involved in axonal guidance are known, including a family of molecules termed netrins. |
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| Also, an increased incidence of axonal swelling was observed in the brain and spinal cord of rats and dogs exposed to high levels of flufenacet. |
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| Dr. Tsai is studying neural repair strategies and axonal regeneration using pluripotent cells, tissue engineering and nanotechnology. |
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| In all but one case, the axonal degeneration observed in these tissues was graded as very minimal and described as rare, scattered vacuoles. |
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| In conclusion, optic nerve axonal injury appears to be a frequent finding in infants who have sustained acceleration-deceleration whiplash-type trauma. |
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| The phenotypic analysis of fru mutant embryos along with fru's temporal and spatial expression pattern suggests that the fru gene functions during axonal outgrowth. |
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| If the brain is experiencing problems completing a task because a specific area of the brain has been affected by axonal loss, it may be able to partially shift the performance of that task to another area of the brain. |
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| Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. |
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| Multiple sclerosis is a chronic, inflammatory medical condition that results in demyelination, axonal transection, and neurodegeneration. |
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| Determination of axonal loss and optic nerve head degeneration in glaucomatous eyes. |
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| Electroneuromyographic examination revealed a peripheric sensorial type polyneuropathy, primarily affecting the axonal component. |
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| Treatment is recommended because of the growing body of scientific evidence that indicates that inflammation, demyelination and axonal loss begin very early in the MS disease process. |
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| Transport from the respiratory zones to the olfactory bulbs and then translocation by axonal migration, may have contributed to transport of nanoparticles. |
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| He postulates that properties of immune components present in MS lesions, or properties of the neural cells, may determine the extent of myelin and axonal injury. |
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| An experimental study of axonal degeneration and barrier damage after intrafascicular injection or topical application of bupivacaine. |
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| Dying back is a form of axonal degeneration in which the axon of an unhealthy neuron progressively degenerates over weeks or months, gradually spreading to the cell body. |
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| For 3 patiens, an electromyogram showed asymmetric axonal neuropathy, and various patterns of nerve involvement were observed. |
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| In one experiment, blocking cytosolic PLA2 in the transected sciatic nerve slowed myelin degradation and axonal deterioration in the distal nerve segment. |
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| From the digitalized images, the axonal counts across the lateral column, as well as total axonal transectional diameter, were obtained. |
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| Types of fatigue in MS myelinated nerve fibers, changes in potassium conductance at the level of the axonal membrane, and increased body temperature with exercise. |
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| Neurofilaments are intraneuronal and axonal cytoskeletal framework proteins. |
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| During this phase, there are generally fewer relapses and less inflammatory activity, but the burden of disease steadily increases because of ongoing axonal damage. |
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| Sustained neurological disability is believed to be due to axonal transection within MS inflammatory plaques and subsequent failure of the neurons to repair themselves. |
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| He suffered a diffuse axonal injury, which specialists say only one in 10 of those severely affected survive and usually in a vegetative state. |
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| Bianchi has been diagnosed with a diffuse axonal injury to the brain, whereby damage has occurred over a widespread area. |
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| The records from various doctors over the past 23 years are filled with mysterious-sounding medical terms: peripheral neuropathy, peripheral motor axonal polyneuropathy, xerosis and hammer toes. |
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| Using a computer model to visualise a nerve cell from a rat's cerebral cortex, researchers have made cell bodies and their dendritic and axonal arbors visible. |
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| Certain forms of acute idiopathic polyneuritis are characterized by severe primary axonal involvement and distinction is made between these forms and the more classic forms which are associated with demyelinization. |
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| The space between cells that is occupied by axonal and dendrite endings is called neuropile. |
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| Changes to the efficacy of individual synapses on the parallel fibers and the Purkinje neurons alter the resulting PSPs in Purkinje axons, generating different axonal spiking frequencies. |
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| If a nerve fibre is severed, the length of axon farthest from the cell body, or soma, will be deprived of the axonal flow of metabolites and will begin to deteriorate. |
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| Motor ganglia have multipolar cell bodies, which have irregular shapes and eccentrically located nuclei and which project several dendritic and axonal processes. |
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| This has the dual advantage of providing a strong axonal donor volume for smile restoration while avoiding synkinetic reinnervation of adjacent musculature. |
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| Marussia driver Bianchi, 25, suffered a diffuse axonal injury to his brain, where the damage is more widespread, following a crash into a recovery vehicle at Suzuka. |
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| Axonal projections extend from this nucleus, innervating nearly every region throughout the encephalon, including the cerebellum. |
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