How to use alkaloids in a sentence

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Sentence Examples The leaves of the plant contain alkaloids, glycosides, triterpenes, tannins, volatile bases and probably other substances. Atropine, digitalis, ergot alkaloids, and diuretics may interact with phenylephrine. Mycotoxins commonly found in grains or feeds used in Nebraska are aflatoxins, ergot alkaloids, fumonisins, vomitoxin and zearalenone. Like most alkaloids, nicotine exerts its effects at receptors for chemicals that transmit nerve impulses. However, in a high-elevation species of columbine, enhanced UV-B radiation appeared to destroy alkaloids. Using high pressure liquid chromatography, the alkaloids can be purified and crystallized. Many clematis are high in poisonous alkaloids, this may also be true of virgin's bower and sweet autumn clematis. Alternatively, endophytes that produce alkaloids also may compete with the plant for nutrients. Tropane alkaloids of medicinal application, such as hyoscyamine and scopolamine are found in a limited number of solanaceous plants. Ephedra alkaloids commonly are combined with caffeine or botanical sources of caffeine for weight loss. The major categories are alkylating agents, antimetabolites, plant alkaloids, anti-tumor antibiotics, and steroid hormones. Various compounds have been identified as substrates such as peptides, vinca alkaloids, anthracyclines, and epipodophyllotoxins, among others. The cinchona tree contains more than 20 alkaloids of which quinine and quinidine are the most important. The vinca alkaloids have been used in cancer therapy for more than 30 years. Benzylisoquinoline alkaloids are ubiquitous among the Papaveraceae, which include the California poppy and the opium poppy. The alkaloids stimulated the vasomotor and respiratory centers in the brain stem of dogs. This biogenetic hypothesis indicates an alternative pathway to produce these metabolites, leading to a new class of indole alkaloids. The major compounds extracted by water were amino acids, peptides, saponins, phenol glycosides, tannins, and alkaloids. Anticancer compounds that are extracted from the periwinkle plant, Vinca rosea, are called the vinca alkaloids. These herbs contain highly toxic alkaloids, including aconitine, which activate sodium channels and over-stimulate cell membranes. Show More Sentences Members of the family produce latex, diverse iridoids, cardioglycosides, and various alkaloids, sometimes cyanogenic, rarely saponiferous. Alkaloids have been described as components of plant defence responses and the two main alkaloids found in cocoa are caffeine and theobromine. Caffeine and theobromine are two naturally occurring alkaloids that are present in plants used to brew beverages in many cultures. This material is a complex mixture of about 20 different alkaloids or nitrogen containing organic bases. Nicotine and tropane alkaloids are formed in the roots and transported to the aerial parts of the plant. At present, the chemical components of this water extract are thought to include only alkaloids, terpenes and pigments. Plant or vinca alkaloids are derived from plants and block cell division during mitosis. Prominent examples are quinolizidine alkaloids, gossypol, glucosinolates, nonproteinogenic amino acids and furanocoumarins. Terpenoid indole alkaloids absorb UV radiation and are implicated as having a UV-protective role in plants. They are precursors of benzoic phenanthridine alkaloids, active ingredients of many medicinal plant extracts. Key alkaloids present in goldenseal include berberine, hydrastine, and canadine. Caffeine is a naturally occurring drug belonging to a group of compounds called alkaloids. They contain the highly toxic C19 diterpenoid alkaloids of aconitine, mesaconitine and hypaconitine. The conditions for determining the total greater celandine alkaloids resulting from a plant by acid infusion were studied. Detection of ergot alkaloids in stomach or rumen content is evidence of exposure. Other alkaloids that have been identified in hemlock are methyl coniine, ethyl piperidine and pseudoconhydrine. Pyrrolizidine alkaloids present in comfrey tea and other plant materials are widely recognized as hepatotoxins. Tryptophan is used in some plant species as a precursor to bioactive alkaloids and defence phytoalexins, as well as the phytohormone auxin. The tropane alkaloids scopolamine and hyoscyamine were extracted and analysed from N. tabacum cultured hairy roots. Because of their ability to cause peripheral vasoconstriction, ergot alkaloids should not be used chronically. Show More Sentences The endophyte produces ergot alkaloids that have been linked to decreased animal performance as well as toxicity problems. Most alkaloids are also chiral molecules, meaning they have nonsuperimposable mirror images. This manuscript reviews the history and pharmacognosy of opium, and describes the chemistry, pharmacology, and therapeutic uses of the major opium alkaloids. Chemical analysis of lupulin reveals bitter substances, including the alkaloids codeine and morphine, which are responsible for the bitter flavor of hops. Excessive amounts of these materials, which contain diterpene alkaloids particularly aconitine, can produce toxic effects and occasional fatalities. Quinine and caffeine are two distinguished carriers of such alkaloids. Besides reserpine, other alkaloids used in hypertension and other cardiac disorders are ajmaline, rescinnamine, serpentinine, sarpagine, deserpidine, and chandrine. Compounds in cat's claw called pentacyclic alkaloids have been shown in test-tube studies to have anti-viral, anti-inflammatory and detoxification properties. Other important alkaloids are caffeine, ricinine, and quinine. Diuretics can be found in terpenes, phenolics and alkaloids. Many multicellular trichomes are glandular, developing a terminal gland which may secrete a variety of compounds, such as alkaloids to deter or poison predators. These alkaloids are produced when our bodies metabolise beer, wine or spirits, and have been found in chocolate at concentrations of as high as 7 micrograms per gram. Fusing rods and metal pieces into architectonic structures, he often treated the surfaces with droplets of metal or with acids and alkaloids to achieve variations in color. Anthocleista nobilis contains the alkaloids brucine and loganine and has been noted to be antispasmodic and neurotropic, having a marked hypotensive effect. Active cytotoxic agents for patients with advanced KS with the longest track records include vinca alkaloids, anthracyclines, bleomycin, and etoposide. Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors. Gamila W, Bassem EM, Atta S, Gama M Toxic pyrrolizidine alkaloids of certain Boraginaceous plants. The taxanes and vinca alkaloids target that part of the cytoskeleton known as microtubules. For example, certain drugs, such as the alkaloids, are notoriously difficult to solubilize. Multidrug resistance-associated protein 2 is involved in the efflux of aconitum alkaloids determined by MRP2-MDCKI1 cells. Show More Sentences The main psychoactive alkaloids present at various times in khat leaves are the phenylpropylamines cathinone, cathine and norephedrine. The second part strategically applies the intramolecular diamination of indoles to synthesize naturally occurring dimeric indole alkaloids. As with all Amarylidaceae genera, Narcissus contains unique isoquinoline alkaloids. Hemanthamine, Tazettine, Narciclasine, Montanine and Galantamine alkaloids are also represented. The distribution of alkaloids within tissues may also reflect defence against parasites. The rodent repellant properties of Narcissus alkaloids have been utilised in horticulture to protect more vulnerable bulbs. Of all the alkaloids, only galantamine has made it to therapeutic use in man, as the drug galantamine for Alzheimer's disease. Many species produce bioactive compounds called mycotoxins, such as alkaloids and polyketides, that are toxic to animals including humans. These alkaloids protect grass plants from herbivory, but several endophyte alkaloids can poison grazing animals, such as cattle and sheep. For instance, ornate moth caterpillars utilize pyrrolizidine alkaloids that they obtain from their food plants to deter predators. The mixture contains harmine, harmaline, and tetrahydroharmine, alkaloids that are also MAO inhibitors. The remaining alkaloids in the latter cultivar are primarily narcotoline and noscapine. Seed capsules can be dried and used for decorations, but they also contain morphine, codeine, and other alkaloids. Rather, the prepared opium is indirectly heated to temperatures at which the active alkaloids, chiefly morphine, are vaporized. Unlike many other Solanaceae species, they do not contain tropane alkaloids, which are often poisonous to humans and other animals. Isolation and characterisation of the monoterpenoid indole alkaloids of Aspidosperma pyrifolium. High up in the Andes Mountains of South America, one of the few sources of food is a wild potato that also has bitter alkaloids. Cholinesterase inhibitory and anti-amnesic activity of alkaloids from Corydalis turtschanimovii. Oxoaporphine alkaloids and quinones from Stephania dinklagei and evaluation of their antiprotozoal activities. Rarely, anaphylactoid reactions have been reported when morphine or other phenanthrene alkaloids of opium are administered intravenously. Show More Sentences Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyma speciosa. Three new pseudodistomins, piperidine alkaloids from the ascidian Pseudodistoma megalarva. Antitumour properties of acridone alkaloids on a murine lymphoma cell line. Ephedra contains alkaloids including ephedrine, pseudoephedrine, norephedrine, methylephedrine and norpseudoephedrine. New protopine and benzyltetrahydropeotoberberine alkaloids from Aristolochia constricta and their activity on isolated guinea-pig ileum. Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats. Veratrum alkaloids and distal inhibitors of cholesterol biosynthesis are teratogens that have been associated with holoprosencephaly. The pathogen's sporangia, or sporeforming structures, were also exposed to the two alkaloids. Chemistry and pharmacology of analgesic indole alkaloids from the rubeaceous plant, Microgyria speciosa. This important group of alkaloids include morphine, codeine, oripavin, thebaine, papaverin and other important pharmaceutical alkaloids. Coadministration is contraindicated for ergot alkaloids, terfenadine, astemizole, cisapride, pimozide, halofantrine, and quinidine. The alkaloids in ragwort are very potent hepatotoxins and cause a characteristic form of liver damage which is irreversible and untreatable. The proposal aims at addressing the collective syntheses of a series of bioactive indole alkaloids from a common intermediate. Antibacterial benzofuran neolignans and benzophenanthridine alkaloids from the roots of Zanthoxylum capense. Reserpine alkaloids are present in root, stem, leaves and seeds of plant and percentage of alkaloids depends on the geographical place from where the plant is collected. It is blamed on exposure to calcium oxalate, chelidonic acid or alkaloids such as lycorine in the sap, either due to a direct irritant effect or an allergic reaction. Furthermore, Roney-Dougal has proposed that the psychoactive harmala alkaloids also found in ayahuasca, such as harmaline, are responsible for producing ESP-like experiences. Despite the lethal potential of Narcissus alkaloids, they have been used for centuries as traditional medicines for a variety of complaints, including cancer. The separation of the alkaloids can be conveniently and very accurately effected gravimetrically or volumetrically by means of silver theobromide. The alkaloids cytisine and sparteine are derivatives of quinolizidine. Show More Sentences Phytochemical contents of the leaves included presence of terpenoid glycosides, protein, carbohydrates but absence of alkaloids and steroids Kumar et al. Quaternary isoquinoline alkaloids sanguinarine and chelerythrine. Chemotaxonomy and geographical distribution of tropane alkaloids. Such term does not include the isoquinoline alkaloids of opium. Toxic pyrrolizidine alkaloids of certain Boraginaceous plants. Various anthraquinones and their derivatives, emodin glycosides, toxalbumins and other alkaloids are the few compounds blamed for the cassia toxicity. They contain a pharmacopoeia of drugs including alkaloids, glucosides, phytotoxins, selenium and a host of other toxins that induce a variety of symptoms. All species of yew contain highly poisonous alkaloids known as taxanes, with some variation in the exact formula of the alkaloid between the species. Throughout history the scent of narcissi has been an important ingredient of perfumes, a quality that comes from essential oils rather than alkaloids. Nearly 100 alkaloids have been identified in the genus, about a third of all known Amaryllidaceae alkaloids, although not all species have been tested. For example, ergot alkaloids are the metabolic products of fungi genera such as Claviceps, Penicillium, Rhizopus, and Aspergillus, as well as higher plants and marine animals. One of these alkaloids, called harmine, inhibits a protein known as DYRK1A, which has been implicated by this and other studies in the formation of tau phosphorylation. The drugs vinblastine and vincristine are vinca alkaloids, used to treat Hodgkin's disease, leukemia, and other cancers, were derived from the Madagascar periwinkle. University professor Bill Ayer's, FCIC, work in natural product isolation began with the lycopodium alkaloids and later included insect pheromones. The purpose of this study was to investigate the underlying mechanism of the total alkaloids from Mahonia bealei in treating pyloric ligation-induced gastric ulcers in rats. One of the best and most well-known is the combination of metallic platinum with cinchona alkaloids, which catalyzes the hydrogenation of only one face of methyl pyruvate. In our study, the phytochemical analysis of the extract showed the presence of alkaloids, carbohydrates, proteins, aminoacids, phenols, starch and saponins. Examples from Classical Literature The chief constituents of colchicum are two alkaloids, colchicine and veratrine. Of all the dangers to be met with in superstitious countries, these mydriatic alkaloids are among the worst. Papaverine, laudanosine, narcotine, and narceine are four other alkaloids found in opium. Quinine, sulphate and bisulphate of, and all alkaloids or salts of cinchona bark. Quinine is the most useful of these alkaloids, and this is found in greatest quantities in calisaya bark. If it is chemically pure, cinchonidine belongs to the non-fluorescent alkaloids. The alkaloids produce a disease known as ciguatera, characterized by paralysis and gastric derangements. Its meythl ester, which can be formed from it, is codeine, one of the accompanying alkaloids of opium. It must not be supposed that no syntheses of alkaloids have been effected as yet. Niobe was an ideal herbarium for growing the swampland plant from which the complex of alkaloids was extracted. Turning now to the non-volatile and oxygenized bases, we take up first the opium alkaloids. Both contain stimulating alkaloids, theobromine and caffeine, and fat is a notable constituent of cocoa. They are all, like atropine, mydriatic alkaloids, so-called from the effect on the eye. Claude Bernard thought it the most somniferous of the opium alkaloids. Indole alkaloids of a Thai medicinal herb, Mitragyna speciosa, that has opioid agonistic effect in guinea-pig ileum. This is the same target of the most widely used chemotherapy drugs in cancer, the taxanes and vinca alkaloids. Over 50 different indole and indoline alkaloids have been isolated in this plant. In addition to tropane alkaloids key products include Calcium sennosides, Colchicine, Enoxolone, Hysocine-N-Butylbromide, Nicotine, Thiocolchicoside and Vinpocetine. Find more words! 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What is the adjective for alkaloids? What is the noun for alkaloids? Use our Sentence Generator Nearby Words alkaloidal alkaloid alkalizing alkalized alkalization alkalising alkalosis alkane alkanes alkanet alkaptonuria alkene 9-letter Words Starting With a al alk alka alkal alkalo alkaloi alkaloid