The concept of dominance and recessiveness is not particularly relevant in X-linked inheritance. |
|
Female carriers of X-linked recessively inherited disorders can often be identified by some outward expression of the disorder. |
|
So imprinting of X-linked genes naturally results in sexually dimorphic gene expression. |
|
However, results for X-linked loci are also generally applicable to any haplodiploid genetic system. |
|
Like hemophilia A, hemophilia B, or factor IX deficiency, is an X-linked chromosome bleeding disorder. |
|
For this reason, X-linked conditions like hemophilia or muscular dystrophy are expressed in sons and transmitted by physically normal carrier mothers. |
|
These defects, which include conditions such as hemophilia and color-blindness, are called X-linked because the genes are carried on the X chromosome. |
|
The researchers tackled a condition called X-linked retinitis pigmentosa, a genetic defect that is passed from mothers to sons. |
|
The method would therefore be amenable to screening an X-linked dominant disorder with heterozygous females and hemizygous male patients. |
|
Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease. |
|
Abnormal genes that are located on X chromosomes result in X-linked disorders, like haemophilia. |
|
Wildin RS, Ramsdell SF, Peake J, Faravelli F, Casanova JL X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. |
|