| This suggests that the Cu ion may interact with electronically excited Trp partially quenching its fluorescence. |
|
| The effects of the membrane are clearly illustrated by the increased frequencies of hydrogen-bonding rotamers and the snorkeling of Trp and Tyr out of the membrane. |
|
| In particular, the coupling constant associated with fluorination of Trp, 3 in gA,, was found to be consistent with expectations from molecular modeling. |
|
| Peptides such as methionine enkephalin and leucine enkephalin and the proteins chignolin and TRP Cage are examined in this study. |
|
| These include purinergic receptor antagonism, TRP channel antagonism, cannabinoid receptor agonism, melatonin modulation and apoptosis-inducing agents. |
|
| Our first aim will be to characterise the role of Calmodulin binding sites and other unknown regulatory sites on TRP and TRPL, in the feedback loops described above. |
|
