| The distinctive blue and yellow 94-seat Megabus vehicles carry almost twice as many passengers as a traditional express coach. |
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| Coach services running through Sheffield are operated by National Express and to a lesser extent Megabus, part of the Stagecoach Group. |
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| Two Megabus services, the M12 and M20, call at Sheffield en route to London from Newcastle upon Tyne and Inverness respectively. |
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| National Express and Megabus provides direct services to major cities such as Swansea, London, Newcastle upon Tyne and Manchester. |
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| Megabus also operate services in the city, running eastbound to London via Cardiff and Newport, and westbound to Pembroke Dock. |
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| Megabus run buses from the bus station to places north and south of the city. |
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| There are also many intercity bus services offered by Megabus, Citylink and National Express. |
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| Intercity bus travel is provided by Greyhound, Megabus, and Amtrak Thruway Motorcoach. |
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| Megabus and Scottish Citylink operate a regular coach service to the Scotland's capital Edinburgh with connections to Glasgow at Perth. |
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| A couple of private bus companies such as Eurolines, Megabus and Flixbus operate from the Dampoort bus hub. |
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| Interstate bus service is provided by Peter Pan Bus, Greyhound Bus and Megabus. |
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| All Megabus arrivals and departures are at the corner of Columbus Boulevard and Talcott Street on the opposite side of downtown. |
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