| It was found that the majority of silencing occurred following DNA replication, coincident with M phase. |
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| Fluorouracil induces apoptosis by inhibition of the enzyme thymidylate synthase during DNA replication. |
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| For S-phase to occur, chromatin must be primed to initiate DNA replication at sequences called origins of replication. |
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| This defective recovery of DNA replication suggests an inability to coordinate lesion bypass or to initiate new replicons. |
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| Acyclovir is an acyclic guanosine analog that inhibits viral DNA replication of infected cells. |
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| Without this slight imperfection in the mechanism of DNA replication we would still be swimming round in the primeval soup. |
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| In these mutants, the meiotic products remain in interphase in unfertilized eggs and undergo inappropriate DNA replication. |
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| Joanna is also determining the effects of the radiation on DNA replication by using an absorption cytophotometer. |
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| Nonpolar nucleoside isosteres have proven broadly useful in the study of DNA replication by a wide variety of polymerase enzymes. |
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| The same base pairing rules that control the accuracy of DNA replication apply to the process of transcription. |
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| Centrioles duplicate at a precise time in the cell division cycle, usually close to the start of DNA replication. |
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| Dawkins' evolutionary model relies on random mutations in single nucleotides during DNA replication, totally unguided, followed by selection of the fittest by the environment. |
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| It plays a role in cell division, DNA replication and messenger RNA transcription. |
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| The early gene family encodes factors required for meiotic DNA replication, chromosome pairing, synaptonemal complex formation, and meiotic recombination. |
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| Little is known about the architecture and biochemical composition of the eukaryotic DNA replication fork. |
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| Several studies suggest that BLM is involved in restarting DNA replication when a replication fork stalls. |
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| Recent studies in Xenopus have shown a role for DNA replication in the recruitment of topoisomerase II to the chromosomes to facilitate condensin assembly and condensation. |
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| Because the genetic complement of the resultant daughter cells must be the same as the parental cell, DNA replication must possess a very high degree of fidelity. |
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| These drugs interfere with the double helix zip-unzip-zip-again process of RNA and DNA replication. |
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| Endoreduplication: a process in which after an S period of DNA replication, the nucleus does not go into mitosis but starts another S period. The result is chromosomes with 4, 8, 16,chromatids. |
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| Before blastocyte stage when one cell develops to eight-cell stage, passive demethylation takes place due to failure of maintenance methylation that usually follows the DNA replication. |
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| Topoisomerases are required for many processes involving DNA, such as DNA replication and transcription. |
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| Throughout his training, he maintained a strong interest in the molecular mechanisms that help package histones and DNA into chromosomes during DNA replication. |
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| A cell-free system for initiating DNA replication under cell cycle control, including S phase cytosol or a fraction thereof in which are co-incubated G1 phase nuclei, and S phase nuclei or a fraction thereof. |
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| During cell division these chromosomes are duplicated in the process of DNA replication, providing each cell its own complete set of chromosomes. |
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| This inhibits both transcription and DNA replication, causing toxicity and mutations. |
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| In alternative fashion, a cell may simply copy its genetic information in a process called DNA replication. |
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| A brief overview of DNA replication follows, using the LEGO DNA structure as a simulation aid. |
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| The experiment has progressed, and several of the flasks now contain mutator strains, bacteria that have defects in their DNA replication system. |
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| The initiation of DNA replication is linked both to cell cycle progression and chromatin organization. |
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| During oogenesis, discrete sites within the fruit fly genome undergo repeated rounds of DNA replication. |
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| Within the context of a living cell, DNA replication by polymerases also initiates from primer sequences, but without either of these methods. |
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| Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos. |
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| Enzymes can also bind to DNA and of these, the polymerases that copy the DNA base sequence in transcription and DNA replication are particularly important. |
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| These enzymes are also needed to relieve the twisting stresses introduced into DNA strands during processes such as transcription and DNA replication. |
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| Quinolones have a bactericidal effect when these bind with two target enzymes, DNA gyrase and topoisomerase IV, which are essential for DNA replication within the cell. |
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