| Addex's competence in drug development and its expertise in allosteric modulation were recognised in a collaboration established in 2004 with Ortho-McNeil Pharmaceutical, Inc. |
| Addex Pharmaceuticals discovers and develops allosteric modulators for human health. |
| All of the interacting proteins and protein enzymes involved in allosteric regulation are controlled by gene expression. |
| Although numerous allosteric enzymes were studied, much less information is available concerning the coordinated regulation of activities in multienzymatic complexes. |
| Frequently, an end-product of a metabolic pathway serves as an allosteric inhibitor on an earlier enzyme of the pathway. |
| These mechanisms include allosteric regulation, regulation by reversible covalent modification and regulation by control proteins such as calmodulin. |
