How to use peptides in a sentence

Looking for sentences and phrases with the word peptides? Here are some examples.

Sentence Examples Consequently, particular sets of correlated peptides serve to define particular sets of homologous protein motifs within the data set. Therefore, these antimicrobial peptides might make an excellent weapon in the fight against multiply drug-resistant bacteria. Shortterm adjustments of the stomatogastric ganglion motor neurons by neural inputs, peptides, and other neuromodulators are well documented. The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane. For ACO genes, four degenerate oligos were synthesized on the sequences of three different conserved peptides. Various compounds have been identified as substrates such as peptides, vinca alkaloids, anthracyclines, and epipodophyllotoxins, among others. Cnidarians contain chemical synapses and release neurotransmitters, including biogenic amines and peptides. These peptides selectively interact with negatively charged bacterial membranes by electrostatic interaction. In vitro, these peptides inhibited cytotoxicity and differentiation of cytotoxic T cells. Earlier studies indicated that the fibrils themselves were the cytotoxic form of amyloid peptides. They show considerable sequence homology to pleurocidins, antimicrobial peptides of the flounder, Pseudopleuronectes americanus. It is proposed that endogenous opioid peptides can activate PAG output neurons by inhibiting an inhibitory interneuron. The average experimental residue pKs are slightly stabilized relative to what is found in small peptides with a modest standard deviation. Further work is needed to establish whether the homologous CCK and gastrin act as separate peptides in dogfish sharks. Chemical constituents include keratin and eukeratin as well as other proteins, peptides and free amino acids. Peptide bond formation is a condensation reaction leading to the polymerization of amino acids into peptides and proteins. For the synthetic studies, we made the peptides by polymerising an activated form of the amino acid using a nucleophile as an initiator. To compare the deuterium contents of the different peptides, an averaged mass was obtained by centroiding the envelope of isotopic peaks. Colostrum is rich in anabolic peptides, protective antibodies and immune messengers that help the gut heal. One example is the antihypertensive effect of dietary peptides derived from milk protein, mediated by angiotensin converting enzyme inhibition. Show More Sentences All the conjugated peptides were injected together in white rabbits as antigens for antibody production. These results are discussed with respect to the mechanism of membrane disruption by antimicrobial peptides. Mammals make more than 500 antimicrobial peptides, and their ancestry dates back some 300 million years. Thus, we believe that the discovery of the crystalline phase is an important new development for the field of antimicrobial peptides. At this stage, the fusion peptides are displaced from their original position, with one fusion peptide moving toward the viral membrane. Fig. 9 shows the average hydrogen bond lifetimes of each amino acid in the sampled peptides. The topical application of specific peptides helps soften lines and wrinkles around your mouth, eyes and forehead. Titin, however, consists of multiple folded modules connected by short linker peptides. Again, even if such peptides are discovered, their relationship to autism remains entirely speculative. The major compounds extracted by water were amino acids, peptides, saponins, phenol glycosides, tannins, and alkaloids. In vertebrates, the smallest number of research citations on these peptides are commonly in the cyclostomes and elasmobranchs. Circular dichroism in 10 mM phosphate was used to determine the secondary structure and thermal stability of tropomyosin model peptides. The organism requires a complex mixture of organic substrates for growth, including fermentable carbohydrates and peptides. The composition of peptides was determined by amino acid analysis using the phenyl isothiocyanate method. Despite having similar secondary structures, these peptides show different levels of activity and selectivity. If all the peptides present in a single propeptide are processed and released this would lead to a complex secretagogue. Recombinant human elastin peptides coacervate in heated solutions to form fibrillar aggregates. A number of such DNA-binding peptides conjugated to intercalating dyes have been synthesized and characterized in the authors' laboratory. Like others of these peptides, glucagon is expressed in the brain stem and hypothalamic neurons. Normally the hypothalamus coordinates the activity of the pituitary gland through the secretion of peptides and amines. Show More Sentences Hypocretin peptides are neurotransmitters that play an important role in regulating sleep and appetite. These charges cause attraction between neighbouring peptides and result in the formation a hydrogel that swells in the presence of water. In this paper, we will use melittin as an example to see if the proposed theory also describes peptides that form toroidal pores. Transport of peptides and amino acids has been demonstrated in scutella isolated from barley, wheat, rice, and maize. These peptides are composed of amino acids, but are much smaller than proteins. Endogenous antimicrobial peptides can suppress bacterial growth for 3 to 6 hours. Hydration plays a major role in the orientation of peptides in lipid bilayers. There is much interest in understanding the interaction of peptides with lipid bilayers at atomic detail. During phagocytosis, this binary system combines to generate active antimicrobial peptides. The binding of peptides to lipid bilayers is a subject of great interest, from both a biomedical and biophysical standpoint. The purpose of digestion is to break down complex molecules into simple ones such as sugars, fats, and peptides. Similar levels of T cell proliferation were observed on stimulation with either homologous or heterologous peptides. The first, Combination A, contained an enzymatically rendered fish protein with a high level of bioactive peptides and amino acids. Lipidation of bioactive peptides has been proposed as a way to increase their membrane binding, biological activity, and bioavailability. Pert states that peptides and other informational substances are the biochemicals of emotion. The primary structure of peptides and proteins refers to the linear number and order of the amino acids present. This server provides a computerised approach to the design of heteroclitic peptides, using the additive method to calculate affinities. Finally, some peptides may generate pores that admit water but do not allow osmotically active substances to pass. Natriuretic peptides are a group of hormones playing important roles in cardiovascular and osmoregulatory systems in vertebrates. Proteins and peptides would be more accurately defined in high-dimensional space by orthogonal axes representing truly independent characters. Show More Sentences The reason for the relatively low helicity of long peptides is unclear to us. They then added the enzyme trypsin to carve up the remaining proteins into small, but still recognizable fragments, or peptides. Accordingly, I started preparing and characterizing tryptic hemoglobin peptides that contained the highly visible heme group. The peptides seem to form metastable films which can be compressed to relatively large surface pressures. The syntheses of 4-aminomethyl-phenylazobenzoic acid as well as of the linear, monocyclic, and bicyclic AMPB peptides were reported elsewhere. These peptides and FMRFamide excite the muscle cells and fibers of tubellarians, digeneans, and monogeneans. This occurs because the strong interactions of PA molecules with the peptides can pull PA molecules out of the monolayers. When digested, the seed meal released bioactive peptides, or proteins, that inhibited the production of an enzyme that contributes to high blood pressure. It was found that some species of adsorbed proteins or peptides insert in such a way as to form pores at a sufficiently high adsorbate concentration. Many peptides and proteins interact strongly with amphiphilic molecules and these interactions are of vast importance, not only in vivo but also in technical applications. A potential added benefit of such a strategy is the ability of natural antimicrobials to act synergistically with other host defense peptides and proteins. Ampb peptides are a new class of molecules where the photoisomerizable dye azobenzene is linked to the peptide moiety via a flexible methylene spacer. Partly it may be due to its production of the so-called enterocins, a family of bacteriocins, which are antimicrobial peptides produced by some bacterial strains. On the other hand, for a system of four peptides, there are six ways to form dimers, four ways to form trimers and monomers, and only one way to form a tetramer. Are there potential uses for antimicrobial peptides from tunicates? Increased natriuresis is the main feature of these peptides, and this could be a mechanism to counteract increasing volume overload and right heart failure. The peptide subfamily of GPCR contains receptors that bind a disparate array of peptides, such as angiotensin, bradykinin, opioid, somatostatin, and chemokines. Researchers found that hormones and peptides such as estrogen, progesterone, oxytocin and vasopressin played a big role in how well these animals cared for their young. The key issue of this paper is to relate thermodynamics data, especially calorimetric data, of peptide-containing membranes to the aggregation of the peptides. Classically, endocrine hormones are considered to be derived from amino acids, peptides, or sterols and to act at sites distant from their tissue of origin. Show More Sentences In any cases, we do not observe formation of organized protein oligomers in the lipid monolayer as described for pore-forming peptides and proteins. Included among these are the cecropins, a family of peptides typically 33-39 amino acids in length first isolated from the silk moth, Hyalophora cecropia. On the basis of broad structural characteristics, amphibian antimicrobial peptides have been grouped into superfamilies, each being differentiated into various families. The cells produced potent stimulation of allogenic T cells and syngeneic T cells specific for purified protein derivative in the absence of exogenous peptides. Proteins' maddeningly intricate and all too permutable chains of peptides and amino acids were at the heart of the challenge of creating their new approach. Antibiotic peptides constitute a major component of the innate defense system shared by organisms from throughout the phylogenetic tree, including humans. These peptides also inhibited proliferation, angiogenesis, and ERK activation induced by basic fibroblast growth factor with similar potency and efficacy. These interesting properties have made gramicidin an appropriate model for studying solvent effects on the structural changes of peptides and proteins. The enthalpy and entropy of folding for the tropomyosin and troponin T peptides were determined from the change in ellipticity as previously described. The central hypothesis of this study is that proteolytic activity in the tumor microenvironment may liberate peptides that enter the circulation. The present study sought to determine the proportions of thiol-containing amino acids and peptides bound to albumin and globulins. Any fixed width cluster has the potential to misgroup peptides from multiple genes into a single group. Gluten is a protein in grains like wheat, rye and barley that contains gliadin peptides. The technique of chemically assisted fragmentation was used to obtain de novo amino acid sequence data from tryptic peptides. Atrial natriuretic peptide is a member of the family of natriuretic peptides, and regulates diuresis and natriuresis. The interaction of the target protein with Adlyfe's proprietary peptides produces a conformational change that transduces a fluorescent signal. Such peptides were originally synthesized as copies of metenkephalin peptides. Such molecules share the multidimensional signature of antimicrobial peptides. The company focuses on the analysis of mass spectrometric and other analytical data on proteins, peptides and glycans. This luxurious rejuvenator balances skin pH levels and builds collagen with peptides. Show More Sentences The fourth presentation reported the development of a rapid one-step, lyophilized kit to radiolabel peptides with 18F at high specific activity. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. A gemini amphiphile made of natural fatty acid and several peptides, the new material has high permeability. They were comprised of proteinase and its inhibitors, antimicrobial peptides, lectin, and others. Some of the most promising anti-wrinkle, anti-aging products contain peptides. Certain peptides secreted by the bacteria themselves bind to a receptor called AgrC and trigger the bacteria to make toxins. Purification and identification of angiotensin converting enzyme inhibitory peptides from beef hydrolysates. Modifications of peptides with non-natural amino acids to increase stability. Iodination of proteins, glycoproteins and peptides using a solid-phase oxidizing agent, 1,3,4,6-tetrachloro-3a-diphenyl glycoluril. No notable antibody reactivity was found to the noncitrullinated control peptides. NeuroVax, which combines three TCR peptides with IFA, was designed to increase the likelihood of this immune reaction. Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes. Orexins are peptides best known for their role in regulating the sleep-wakefulness cycle, during which they promote wakefulness. For the US2-3xHA immunoisolations, only peptides with a significance score greater than 20 were considered for subsequent analysis. Increased production of orexin A and MCH, which are both orexigenic peptides, may explain the increased food intake observed in HP mice. NeuBiotics are antisense antibiotics composed of relatively short NEUGENE antisense polymers covalently linked to bacteria-permeating peptides. Citrullinated peptides are found in the synovial membranes of many arthritis patients, but only RA patients produce anti-CCP antibodies. Both human and rat ghrelins are 28 amino acid peptides, in which Ser3 is modified by a fatty acid, primarily n-octanoic acid. Also provided are methods of inhibiting HIV-1 production in a cell, or spread of the HIV-1 to another cell, by treating the cells with the above peptides or vectors. A particularly important PTMscan, called Phospho-PTMscan enables the automated detection and localization of phosphorylations of peptides and small proteins. Show More Sentences The frog's skin also secretes temporin, a tarlike mixture of various peptides, for which the latter part of its scientific name is denoted translated in Latin. Researchers have identified several peptides which are necessary part of body systems that could be used for pharmacological purposes during disease incidence. The major peptides that stimulate feeding are orexins A and B, which are secreted by the hypothalamus, and ghrelin, which is secreted by the stomach. In beta sheets, peptides line up in parallel zigzags called beta strands. Neurohormonal peptides were initially described by Henry and Pearce in 1956 after they noted uresis following the inflation of a balloon placed in a dog's atrium. Available July I and co-developed with DiagnoSwiss SA, the OFFGEL Fractionator fractionates intact proteins and peptides by isoelectric point and can run samples in parallel. Wrinkle treatments, such as Unwrinkle, that contains a blend of powder, wrinkle-fighting peptides, neuropeptides, vitamins and moisturizers, is also highly popular. Included were peptides that fold into a beta-pleated sheet structure. These class II major histocompatibility complex proteins present the peptides to immune cells called helper T cells, which coordinate the body's response. This peptide stimulates feeding through neuropeptide Y, agouti-related protein, and orexigenic peptides co-localized in neurons of the hypothalamic arcuate nucleus. Mucins and TFF peptides of the tear film and lacrimal apparatus. First, the scientists conjugated various synthetic peptides, homologous to the gluten amino acid sequence, to keyhole limpet hemocyanin, a carrier protein. The proteins can be more easily identified after the band or spot is cut out, at which point they are digested with enzymes into smaller peptides. Herein, I propose to develop rigid, tricyclic peptides that should, due to a more defined three-dimensional structure, bind to flat surfaces similar as antibodies. These new peptides activate stereospecifically the enzyme responsible for cholesterol esterification in the blood, a key factor in the reverse lipid transport pathway. Among many strategies, studies on natural and artificial amphipathic peptides acting on membranes of microorganisms have yielded promising results. Examples from Classical Literature Putrefactive bacteria, for example, were incubated for an hour with the artificially produced antimicrobial peptides. Find more words! 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Words that rhyme with peptides What is the adjective for peptides? What is the noun for peptides? Use our Sentence Generator Nearby Words peptide bond peptide peptidase peptic pep talk pepsinogen peptidoglycan Pepto-Bismol peptone pep up Pepys Pequod 8-letter Words Starting With p pe pep pept pepti peptid peptide