| Before the introduction of troglitazone in 1997 metformin was the only drug able to sensitise target tissues to insulin. |
|
| However, experience with guanidine and biguanides prompted the development of metformin. |
|
| Side effects of metformin include mild nausea, diarrhoea, and abdominal bloating. |
|
| It is indicated for use as monotherapy or in combination therapy with metformin, a sulfonylurea, or insulin in the treatment of type 2 diabetes. |
|
| Pioglitazone and rosiglitazone, both TZDs, are approved for use in combination with metformin, sulfonylureas, glinides and insulin. |
|
| Her medications included metformin, levothyroxine, sertraline, rosuvastatin, and rabeprazole. |
|
| Recent studies have shown that prescribers do not take either CrCl or CHF into account when using metformin. |
|
| He was on various medications for heart failure, including metoprolol, ramipril, spironolactone, torasemide, metformin, and digoxin. |
|
| Cationic drugs increase the risk for lactic acidosis by interfering with the renal tubular transport of metformin. |
|
| We included GLP-1 mimetics, DPP4 inhibitors and TZDs, along with metformin, since those classes have no potential for hypoglycemia. |
|
| The study included 78,241 diabetics treated with metformin and 12,222 prescribed sulfonylureas, matched with 90,463 nondiabetic control subjects. |
|
| Currently, the first-line oral agents for type 2 diabetes are metformin and sulfonylureas. |
|
| Mice treated with paraquat and metformin survived significantly longer than those treated with paraquat only. |
|
| Antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats. |
|
| Treatments used to lower A1c below 7 percent included metformin, sulfonylurea, glitazone, and insulin. |
|
| By 2005, use of sulphonylureas had decreased, with a parallel increase in use of metformin and glitazone. |
|
| The most common oral hypoglycemic agents used in pregnancy include metformin and glyburide. |
|
| Among those patients with a current EF available, six patients were taking a thiazolidinedione and 15 were on metformin. |
|
| Forced overexpression of Axl in LNCaP cells decreased metformin and taxotere sensitivity and knockdown of Axl in resistant cells increased sensitivity to these drugs. |
|
| Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and rosiglitazone or insulin and acarbose in type 2 diabetes. |
|
|
|
| Do metformin and flutamide alone or combination of both improve anthropometric indices and laboratory tests in overweight and obese PCOS patients under hypocaloric diet? |
|
| Insulin sensitiser drugs such as metformin can help the ovaries to be stimulated and monitored to produce ovulation and help with getting pregnant. |
|
| Linagliptin was administered orally once a day in all cases, either on its own, or in combination with metformin or metformin plus a sulphonylurea or pioglitazone. |
|
| Sodium bicarbonate alone usually fails to correct the acidosis, may cause intracellular acidosis and hypernatraemia, and does not remove metformin. |
|
| Similar to the sulfonylureas, the meglitinides nateglinide and repaglinide are oral insulin secretagogues that are used either alone or with metformin for type 2 diabetes. |
|
| The studies assessed linagliptin as monotherapy, as add-on to metformin, as add-on to metformin plus a sulfonylurea, and as initial combination with pioglitazone. |
|
| Metformin is a biguanide that improves peripheral tissue sensitivity to insulin but inhibits hepatic glucose formation. |
|
| Metformin also may interact with medications such as cimetidine, digoxin, amiloride, quinidine, vancomycin, and trimethoprim, and may interfere with vitamin B12 absorption. |
|
| Metformin hydrochloride is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. |
|
| Metformin and phenformin block the peripheral antinociception induced by diclofenac and indomethacinon the formalin test. |
|
| She had diabetes mellitus since ten years ago and took Metformin, Glibenclamide, Losartan, and Atorvastatin. |
|
