| In view of the role played by aneuploidy in carcinogenesis and in human reproductive failure, this omission is perhaps surprising. |
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| Bone marrow cells exhibited chromosome aberrations, aneuploidy, and changes in the mitotic index. |
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| True non-disjunction as a mechanism causing aneuploidy was separately assessed when a bivalent was found in a set of metaphase II chromosomes. |
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| The most direct way to assess chromosomal aneuploidy is to evaluate chromosome numbers in metaphase cells. |
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| In principle, non-disjunction during spermatogenesis could lead to aneuploidy, which might cause fetal death. |
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| The use of ultrasound in conjunction with maternal serum screening for aneuploidy. |
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| Other experts are turning to genetic screening before transfers to cull embryos without aneuploidy. |
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| Only a small percent of early losses related to aneuploidy are due to parental balanced translocations or inversions. |
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| Similarly, the detection of aneuploidy inducers is enhanced if a 24 hour treatment regimen is used with the microtitre method. |
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| During recent years aneuploidy testing has been increasingly performed in cases of IVF without increased risk of affected offspring. |
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| The possibility that screening for aneuploidy and eliminating affected embryos could improve the success score of IVF has been put forward. |
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| Cytokinetic abnormalities in DNA content, such as aneuploidy, haploidy, and tetraploidy, have been found to occur in human cartilaginous tumors. |
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| There may be specific types of mutagens, e.g. aneuploidy inducers, which act preferentially during meiotic gametogenesis stages. |
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| And the ubiquity of aneuploidy in cancers does need explaining. |
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| Objective: To review the obstetrical outcomes associated with abnormally elevated or decreased level of one or more of the most frequently measured maternal serum marker analytes used in screening for aneuploidy. |
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| Although retrospective studies without proper controls seem promising, reliable prospective studies are needed to provide evidence of the clinical value of aneuploidy testing. |
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| In the future, RAD alone may be a suitable tool for prenatal diagnosis for a subset of women undergoing invasive testing solely for an increased risk of fetal aneuploidy. |
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| In a project funded by the Toxic Substances Research Initiative, the method is being used to measure the induction of aneuploidy in mice exposed to trichloroethylene and its metabolites. |
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| Various centromere-specific probes are available for aneuploidy studies. |
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| Partial aneuploidy can also occur as a result of unbalanced translocations during meiosis. |
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| Unlike single gene disorders, diseases caused by aneuploidy are the result of improper gene dosage, not nonfunctional gene product. |
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| They can also carry out a check known as aneuploidy screening, looking at the chromosomal defects. |
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| Use of a cell hybrid test system to demonstrate that benomyl induces aneuploidy and polyploidy. |
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| We also believe that mecanotransduction might be involved in the control of the very last step of cell division, called abscission, whose failure might lead to aneuploidy and cancer. |
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| Multicolor fluorescence in situ hybridization analysis of aneuploidy and diploidy frequencies in 225,846 sperm from 10 normal men. |
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| To exclude the possibility that low and intermediate levels of amplification are due to aneuploidization rather than HER2 gene amplification, a chromosome 17 specific centromere probe should be used to check for aneuploidy. |
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| Although micronuclei can arise from lagging whole chromosomes following interaction of a compound with the spindle apparatus, the micronucleus test may not detect all aneuploidy inducers. |
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| Numerical chromosomal changes leading to clones with euploidy or aneuploidy are classified into groups according to chromosome number. |
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| By changing the activity of thousands of proteins instead of just one or two gene products, aneuploidy can overwhelm a cell's ability to control its division. |
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| The aneuploidy hypothesis, however, appears a worthy successor. In the case of HIV and AIDS, all subsequent research has shown that Dr Duesberg was wrong. |
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| Further mechanistic investigations may be used to assess the nature of cytogenetic changes induced b clastogens and aneuploidy inducers in the mouse lymphorna tk assay. |
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| Scientific review of literature indicates that polyploidy in vitro is induced by many types of insult and does not necessarily reflect a potential for aneuploidy. |
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| The mechanisms that safeguard cells against aneuploidy are of great interest as aneuploidy contributes to tumourigenesis. |
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| Chromosomal aneuploidy is an abnormal number of chromosomes. |
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| Among the analyzed embryos, simple aneuploidy involving single chromosome anomalies was more common among embryos that developed into blastocysts and morulas. |
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| In the practice of reproductive medicine, chromosomal aneuploidy has long been recognized as a significant cause of abnormal prenatal and postnatal development. |
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| The only factor clearly tied to human aneuploidy is a mother's age. |
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| Y chromosome aneuploidy, micronuclei, kinetochores and aging in men. |
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| We used tag data for the X chromosome for male and aneuploid pregnancies and used the specific chromosome present in 3 copies when fetal aneuploidy was present. |
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| Aiding in the identification of mosaic aneuploidy and chimerism. |
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| Aneuploidy of autosomes is not well tolerated and usually results in miscarriage of the developing fetus. |
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