What is the opposite of shot in the arm?

Need antonyms for shot in the arm? Here's a list of opposite words from our thesaurus that you can use instead.

Noun
Opposite of something that arouses activity or energy in someone or something
Noun
Drug causing sedation
Noun
A source of irritation
“The neighbor's barking dog has become a real problem for me when I need to get some sleep.”
Noun
A depressant drug
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