What is the opposite of immaterially?

Need antonyms for immaterially? Here's a list of opposite words from our thesaurus that you can use instead.

In a sufficiently great or important way as to be worthy of attention
“He consumes a significantly large number of calories, but remains trim by being active.”
Opposite of adverb for of no real importance or relevance
Opposite of adverb for spiritual, rather than physical
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