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What is the opposite of holy grail?

The term holy grail typically refers to:

- The legendary cup purported to have been used by Jesus at the Last Supper (when capitalized Holy Grail).

- A thing which is greatly sought after.

There are no categorical antonyms for this term.

However, in the context of something greatly sought after, one could loosely use words describing things which are generally avoided as antonyms, e.g., kryptonite, bane, scourge, etc.

Noun
Opposite of an intention for which something is hoped to be accomplished
“Their indifference may be due to the fact that they see the sheer pointlessness of this program.”
Noun
Opposite of a passionate aspiration or ambition
“He had an aversion to thoughts of having to stay in his hometown for the rest of his life.”
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