| We were able to demonstrate the correction of titin in vitro. |
| Our approach is next tested against computer simulations of a multimodule titin model with anharmonic linkers and then applied to experimental data for the unfolding of titin. |
| Recently it has been suggested that several different regions of titin might play a role in the sensing of stretch in muscle by binding various ligands. |
| Titin, however, consists of multiple folded modules connected by short linker peptides. |
| Molecular elasticity is associated with a select number of polypeptides and proteins, such as titin, Lustrin A, silk fibroin, and spider silk dragline protein. |
| Titin is a giant protein expressed in both skeletal muscles and heart. |
